People with beriberi, a disease caused by a thiamin deficiency, have elevated levels of blood pyruvate...
People with beriberi, a disease caused by a thiamin deficiency, have elevated levels of blood pyruvate and α-ketoglutarate, especially after consuming a meal rich in glucose. How can you explain the rise in these compounds based on this vitamin?
Homework Answers
Thiamine pyrophosphate (TPP), the active form of thiamine, is a cofactor ( Non protein part of an enzyme) for enzyme Pyruvate dehydrogenase complex and alpha-ketoglutarate dehydrogenase. These enzyme play an important role in Krebs cycle. So people with vitamin B deficiency cannot synthesized TPP so they have elevated levels of blood pyruvate and α-ketoglutarate.
Thiamine-------> TPP is cofactor for -----> Pyruvate dehydrogenase and alpha ketoglutarate enzyme
No Thiamine----> No TPP----> Elevated Pyruvate and alpha ketoglutarate level
Add Answer to:
People with beriberi, a disease caused by a thiamin deficiency,
have elevated levels of blood pyruvate...
9.) (4 pts) A thiamine deficiency causes the disease beriberi. The symptoms are pain in the...
9.) (4 pts) A thiamine deficiency causes the disease beriberi. The symptoms are pain in the limbs, weakness of the muscles and distorted skin sensations. The heart becomes enlarged and the cardiac output diminishes. (a) Which of the metabolic pathways that we have studied would be affected by a thiamine deficiency? List the affected enzymes. Pyruvate dehydrogenasc (b) A deficiency of thiamine elevates the blood levels of pyruvate and a-ketoglutarate. How are these effects related to the deficiency? boldog
6. Which group of people in the U.S. is most at risk for thiamin deficiency? Why?...
6. Which group of people in the U.S. is most at risk for thiamin deficiency? Why? 7. What is the name of the thiamin deficiency disease? 8. What are the major symptoms of thiamin deficiency? 9. Which food group contributes the most riboflavin to the diet in the United States? 10. What is the primary source of vitamin D for humans in general? 11. The body can make niacin from the amino acid ___________________________. What does your body generally do...
The people of Malaysia belong to three communities: the local people called Malays, immigrants from South...
The people of Malaysia belong to three communities: the local people called Malays, immigrants from South India called Tamils, and immigrants from China. During the early 20th century, the Malays lived mainly in coastal villages, the Tamils worked on rubber estates, and the Chinese worked in tin mines. In general, the people were very poor and they consumed a limited variety of foods.[1] Rice was the staple diet of all three communities and therefore the key source of caloric and...
Questions 1. Thiamin deficiency was observed only in the Chinese community even though all three communities...
Questions 1. Thiamin deficiency was observed only in the Chinese community even though all three communities had the same staple (rice) diet. Explain. On packages of enriched rice sold in supermarkets, the rice preparation directions state that the 2. rice should not be washed before cooking. Explain. deficiency. Explain. Provide two plausible explanations for what might cause above normal levels of pyruvate in blood 3. Severe metabolic acidosis caused by high levels of lactate is often associated with thiamin 4....
Questions Thiamin deficiency was observed only in the Chinese community even though all three communities had...
Questions Thiamin deficiency was observed only in the Chinese community even though all three communities had the same staple (rice) diet. Explain. 1. On packages of enriched rice sold in supermarkets, the rice preparation directions state that the rice should not be washed before cooking. Explain. 2. evere metabolic acidosis caused by high levels of lactate is often associated with thiamin deficiency. Explain. 4. Provide two plausible explanations for what might cause above normal levels of pyruvate in blood 5....
3 20 The conversion pyruvate to either ethanol or lactate occurs A. when there is an abundance of pyruvate but a deficiency of onygen B. when there is an abundance of BOTH pyruvate and oxygen C....
3 20 The conversion pyruvate to either ethanol or lactate occurs A. when there is an abundance of pyruvate but a deficiency of onygen B. when there is an abundance of BOTH pyruvate and oxygen C. when there is a deficiency of BOTH pyruvate and oxygen D. for the regeneration of NADH so that hydrolysis of ATP can continue to fuel the glycolysis pathway Explain how gluconeogenesis differs from gtycolysis 21 Gluconeogenesis is simply the reverse of all 10 steps...
Phenylketonuria is an inherited disease caused by a recessive allele. People with PKU can't break down...
Phenylketonuria is an inherited disease caused by a recessive allele. People with PKU can't break down the amino acid phenylalanine properly; this compound and a byproduct can accumulate in the blood to toxic levels, causing mental retardation. A man and a woman are both normal, but they are carriers of the disease. A) If they have children together, what proportion of the kids would be expected to have PKU? B) What proportion of their children would be normal?
Consuming too much of vitamin C has serious consequences (True/False). Vitamin C deficiency is called? Where can yo...
Consuming too much of vitamin C has serious consequences (True/False). Vitamin C deficiency is called? Where can you find beta-carotene? What is the difference between carotenoids and retinoids? Cancer is caused by free radicals; therefore, consuming antioxidants could help in preventing cancer True/False) List the nutrients involved in bone healthーーーーーーーーーーーーーーーーー , and Almost 100% of calcium consumed will be absorbed by the body (True/False) Chronic deficiency of calčum that causes some (especially the elderly) to have weak and brittle bone...
26. Why did Jessie’s carnitine deficiency cause her to have abnormally low plasma glucose levels at the end of a fasting...
26. Why did Jessie’s carnitine deficiency cause her to have abnormally low plasma glucose levels at the end of a fasting study, when compared to a healthy person who has fasted for the same length of time? In the absence of carnitine, the liver stores large amounts of glycogen; absorption of glucose to create these stores depletes blood glucose Carnitine acts as a hormone and stimulates glucose release from the liver; lack of carnitine results in loss of hepatic glucose...
A deficiency of the B vitamin niacin can result in which of the following? A beriberi B Wernicke encephalopathy c pellagra D scurvy 1. Which organ contributes to the homeostasis of riboflavin...
A deficiency of the B vitamin niacin can result in which of the following? A beriberi B Wernicke encephalopathy c pellagra D scurvy 1. Which organ contributes to the homeostasis of riboflavin by removing the excess? A kidney B liver C stomach D duodenum 2. 3. How does smoking seem to affect biotin catabolism in women? A increases it decreases it B C changes it into a toxic substance D there is no effect on biotin from smoking The primary...
9.) (4 pts) A thiamine deficiency causes the disease beriberi. The symptoms are pain in the limbs, weakness of the muscles and distorted skin sensations. The heart becomes enlarged and the cardiac output diminishes. (a) Which of the metabolic pathways that we have studied would be affected by a thiamine deficiency? List the affected enzymes. Pyruvate dehydrogenasc (b) A deficiency of thiamine elevates the blood levels of pyruvate and a-ketoglutarate. How are these effects related to the deficiency? boldog
Questions 1. Thiamin deficiency was observed only in the Chinese community even though all three communities had the same staple (rice) diet. Explain. On packages of enriched rice sold in supermarkets, the rice preparation directions state that the 2. rice should not be washed before cooking. Explain. deficiency. Explain. Provide two plausible explanations for what might cause above normal levels of pyruvate in blood 3. Severe metabolic acidosis caused by high levels of lactate is often associated with thiamin 4....
Questions Thiamin deficiency was observed only in the Chinese community even though all three communities had the same staple (rice) diet. Explain. 1. On packages of enriched rice sold in supermarkets, the rice preparation directions state that the rice should not be washed before cooking. Explain. 2. evere metabolic acidosis caused by high levels of lactate is often associated with thiamin deficiency. Explain. 4. Provide two plausible explanations for what might cause above normal levels of pyruvate in blood 5....
3 20 The conversion pyruvate to either ethanol or lactate occurs A. when there is an abundance of pyruvate but a deficiency of onygen B. when there is an abundance of BOTH pyruvate and oxygen C. when there is a deficiency of BOTH pyruvate and oxygen D. for the regeneration of NADH so that hydrolysis of ATP can continue to fuel the glycolysis pathway Explain how gluconeogenesis differs from gtycolysis 21 Gluconeogenesis is simply the reverse of all 10 steps...
Consuming too much of vitamin C has serious consequences (True/False). Vitamin C deficiency is called? Where can you find beta-carotene? What is the difference between carotenoids and retinoids? Cancer is caused by free radicals; therefore, consuming antioxidants could help in preventing cancer True/False) List the nutrients involved in bone healthーーーーーーーーーーーーーーーーー , and Almost 100% of calcium consumed will be absorbed by the body (True/False) Chronic deficiency of calčum that causes some (especially the elderly) to have weak and brittle bone...
A deficiency of the B vitamin niacin can result in which of the following? A beriberi B Wernicke encephalopathy c pellagra D scurvy 1. Which organ contributes to the homeostasis of riboflavin by removing the excess? A kidney B liver C stomach D duodenum 2. 3. How does smoking seem to affect biotin catabolism in women? A increases it decreases it B C changes it into a toxic substance D there is no effect on biotin from smoking The primary...
Most questions answered within 3 hours.
-
A
cylunder of titanium (length = 5.00cm, diameter = 1.20 cm) has a
mass of 25.5...
asked 57 minutes ago -
1) Answer Each question with 1-2 Sentences:
a) How can we use the continuity and change...
asked 1 hour ago -
5. What is the decimal equivalent of the largest binary
integer that can be obtained with...
asked 54 minutes ago -
Why is the magnitude of the Type Ia supernova always the same
(-19.6)?
asked 1 hour ago -
5. You are a quality control engineer and you are
asked to analyze the lifetime (in hours)...
asked 1 hour ago -
How many ways can 2 people be chosen and arranged in a straight
line if there...
asked 2 hours ago -
(Problem 1d). Leandro has 16 hours per day that he can allocate
to work or leisure....
asked 3 hours ago -
Morganton Company
makes one product and it provided the following information to help
prepare the master...
asked 3 hours ago -
2Al + 3Cl2 --> 2AlCl3
If one mole Al is reacted w two moles Cl2, how...
asked 4 hours ago -
1. You will see some trends in the movement of each currency vs.
the US Dollar....
asked 4 hours ago -
9. (9 pts) An investor with a stock portfolio worth several
hundred thousand dollars sued his...
asked 5 hours ago -
Which statement is true?
a. Unless directed otherwise, the computer automatically
executes C. statements one before...
asked 5 hours ago