ZuoTi.Pro
Question

What fraction of Glycine is in the non-charged form at pH= 7. Use pKa values 2...

What fraction of Glycine is in the non-charged form at pH= 7. Use pKa values 2 and 9 to approximate.

science   biology   
0 0
Add a comment Improve this question Transcribed image text
Next > < Previous
Sort answers by oldest

Homework Answers

Answer #1

For the simplest amino acid, glycine, pKa1= 2.34 and pKa2 = 9.6, pI = 5.97. The pI will be at a lower pH because the acidic side chain introduces an "extra" negative charge. So the neutral form exists under more acidic conditions when the extra -ve has been neutralized

The glycine has an overall charge of -1. The isoelectric point or the pI is the pHwhere the molecule is electrically neutral ie. its overall charge is 0. The majority ofglycine molecules will have an overall charge of 0 between the pHs of 2.2 and 9.6.

0 0
Add a comment
Know the answer?
Add Answer to:
What fraction of Glycine is in the non-charged form at pH= 7. Use pKa values 2...
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Log In

Sign Up

Not the answer you're looking for? Ask your own homework help question. Our experts will answer your question WITHIN MINUTES for Free.
Similar Homework Help Questions

  • In a 0.1 M solution of glycine at pH 9.0, what fraction of glycine has its...

    In a 0.1 M solution of glycine at pH 9.0, what fraction of glycine has its amino group in the —NH + 3 —NH3+ form? I know the answer, but can someone explain why the fraction is .25/(1+.25)) x100% = 20%? Where did the (1+.25) come from?

  • In a 0.1 M solution of glycine at pH 9.0, what fraction of glycine has its...

    In a 0.1 M solution of glycine at pH 9.0, what fraction of glycine has its amino group in the -NH3+ form? I can't figure out how to get from 0.25=[NH2]/[NH3] to (0.25/[0.25+1]) x 100 = 20% Why do you divide by (0.25+1) ?

  • The amino acid glycine has pKa values of 2.4 and 9.8. A solution was made by...

    The amino acid glycine has pKa values of 2.4 and 9.8. A solution was made by dissolving 1.15 g of glycine sodium hydrate (shown below) in 100.00 mL of water. The molecular weight of the salt is 115 g/mol 5. Нас .Н20 Na+ H2N What is the pH of the salt solution? 20-mL aliquot of would result, making sure to label at least four sets of values on the graph. a ior itrated with 0.100 M b on curve that...

  • The structure of glycine in its fully protonated form is shown below. Its first pKa is...

    The structure of glycine in its fully protonated form is shown below. Its first pKa is 2.34, while its second pKA is 9.6. What will be the average net charge on glycine molecules in a solution whose pH is 3.34? Explain your answer fully with a combination of words and equations as appropriate! (That's what's written) H3N^+-CH2-COOH Glycine Thanks guys. I missed the review going over this and Im a little anxious as the test is soon. I have the...

  • Draw the structure of a dipeptide of lysine-glycine (in that order!) at a pH of 7....

    Draw the structure of a dipeptide of lysine-glycine (in that order!) at a pH of 7. The pKa for the carboxyl group is 2, for the amino group is 9, and the R group for lysine is 10. Hint: Be mindful of the N and C termini. Amino acid sequences are written in a very specific order.

  • Qa. Positively charged R group (i.e sidechain) at physiological pH (pH=7) *hint: looking for 2 a.a....

    Qa. Positively charged R group (i.e sidechain) at physiological pH (pH=7) *hint: looking for 2 a.a. Qb. Aromatic R group (i.e. sidechain), hydrophobic (non-polar) and neutral at pH <14. *hint: looking for 2 a.a. Qc. The amino acids that have ionizable (i.e. chargeable) sidechains between 0<pH<14. *hint: looking for 7 a.a. listed in alphabetical order by first letter. Qd. State the functional groups and pKa values associated with the amino acid Glu.Answer should be entered as follows: group pKa; group...

  • 20. Properties of a Buffer The amino acid glycine is often used as the main ingredient...

    20. Properties of a Buffer The amino acid glycine is often used as the main ingredient of a buffer in biochemical experi- ments. The amino group of glycine, which has a pKa of 9.6, can exist either in the protonated form (-NH3 or as the free base (-NH2), because of the reversible equilibrium (a) In what pH range can glycine be used as an effective buffer due to its amino group? (b) In a 0.1 M solution of glycine at...

  • strongest acid? pka=8 conjugate base kb=2 pka=4 cb pkb=9 pka=7 what is pH of Cu(ClO4)2 ph...

    strongest acid? pka=8 conjugate base kb=2 pka=4 cb pkb=9 pka=7 what is pH of Cu(ClO4)2 ph of SrCl2 ph NH4OCl

  • Calculate the pH of a 0.254 M solution of ethylenediamine (H2NCH2CH2NH2). The pKa values for the...

    Calculate the pH of a 0.254 M solution of ethylenediamine (H2NCH2CH2NH2). The pKa values for the acidic form of ethylenediamine ( H3NCH2CH2NH3 ) are 6.848 (pKa1) and 9.928 (pKa2). Calculate the pH of a 0.254 M solution of ethylenediamine (HzNCH2CHzNH2). The pK, values for the acidic form of ethylenediamine (H3NCH2CH2NH3) are 6.848 (pKa) and 9.928 (pKa2). Number pH-ID Calculate the concentration of each form of ethylenediamine in this solution at equilibrium. Number [H.NCH,CMNH]D Number Number

  • What about the pKa values of the R groups of the seven amino acids containing an...

    What about the pKa values of the R groups of the seven amino acids containing an ionizable R group? Tyr 10.5 Lys 10.5 Arg 12.5 Asp 3.9 Glu 4.1 His 6.0 Cys 8.4 Indicate the approximate net charge of each of these seven R groups at pH 7.4. Indicate the approximate net charge of each of these seven amino acids at pH 7.4. Note: remember the carboxyl and the alpha-amino group in addition to the ionizable (acidic or basic) R...

ADVERTISEMENT
Free Homework Help App
Download From Google Play
Scan Your Homework
to Get Instant Free Answers
Need Online Homework Help?
Ask a Question
Get Answers For Free
Most questions answered within 3 hours.
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT