In Drosophila, the fused mutation (fu) causes fused wing veins, the tan mutation (t) causes a...
In Drosophila, the fused mutation (fu) causes fused wing veins, the tan mutation (t) causes a tan body, and the garnet mutation (g) causes bright red eyes. All act recessively. A female heterozygous for all three mutations is testcrossed to a male that is fused, tan and garnet, and the following progeny phenotypes were observed:
Phenotype number garnet 279 fused, tan 271 fused, garnet 128 tan 122 tan, garnet 84 fused 66 fused, tan, garnet 30 wild-type 20 Total 1000
Which gene is in the middle?
What are the phenotypic combinations that result from no crossing over (i.e., the non-recombinant or "parental" phenotypes)?
garnet fused, tan fused, garnet tan tan, garnet fused fused, tan, garnet wild-type
What is the map distance in cM between fused and garnet in this cross?
What is the interference (I) observed in this cross?
Homework Answers
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In Drosophila, the fused mutation (fu) causes fused wing veins,
the tan mutation (t) causes a...
Practice 7.1. Cross a female fly with the eyeless mutation (a) for eye shape but normal...
Practice 7.1. Cross a female fly with the eyeless mutation (a) for eye shape but normal bristle (b+) to a male fly with wild type eye shape (a+) with shaven bristles (b). Both of these genes are located on Mate a female fly with mutant traits of a black body (c), bristle (b), and wing veins (v) to a wild- type male (normal body color (c+), bristle (b+), and wing size (v+)]. These three alleles are located on chromosome II...
717 pts). In Drosophila, two recessive mutations delta vein (d) and rough eye (r) both map...
717 pts). In Drosophila, two recessive mutations delta vein (d) and rough eye (r) both map to chromosome 3 and are known to be 20 m.u. apart. Another recessive mutation, garnet eye color (a) has been mapped to the X chromosome. A delta veined, rough and garnet eyed- female was crossed to a wild-type male. The resulting fī females are testcrossed to delta-veined, rough and, garnet-eyed males. dng larg & ORG/ A. (6pts) Write the genotype of the Fı female...
In Drosophila, the X-linked recessive mutation vermillion (v) causes bright red eyes, in contrast to the...
In Drosophila, the X-linked recessive mutation vermillion (v) causes bright red eyes, in contrast to the brick-red eyes caused by the wild-type allele. A separate autosomal recessive mutation, brown (bw), causes flies to have brown eyes. Flies carrying both mutations have no eye pigmentation and are white-eyed. Determine the F1 and F2 phenotypic ratios for each sex from the following crosses: (a) brown females X vermillion males (b) white-eyed females X wild-type males
2. The allele b gives Drosophila flies a black body, and bt gives brown, the wild-type...
2. The allele b gives Drosophila flies a black body, and bt gives brown, the wild-type phenotype. The allele wx of a separate gene gives waxy wings, and wx+ gives nonwaxy, the wild-type phenotype. The allele cn of a third gene gives cinnabar eyes, and cn* gives red, the wild-type phenotype. A female heterozygous for these three genes is testcrossed, and 1000 progeny are classified as follows: 5 wild type, 6 black waxy cinnabar, 69 waxy cinnabar, 67 black, 382...
Mapping genes with recombination frequencies in Drosophila 1. Suppose you know of three linked loci on...
Mapping genes with recombination frequencies in Drosophila 1. Suppose you know of three linked loci on the Drosophila X chromosome (a, b, and c). Assume that you are starting out with true-breeding stocks that show all three recessive traits and true-breeding stocks that show all three dominant traits. A. If you wanted to do a 3-point test cross to map the three loci, how would you set up the cross? What genotypes do you use for males and females in...
In Drosophila, the autosomal recessive brown eye color mutation (b) displays interactions with both the X-linked...
In Drosophila, the autosomal recessive brown eye color mutation
(b) displays interactions with both the X-linked recessive
vermilion mutation (v) and the autosomal recessive scarlet (s)
mutation. Flies homozygous for brown and simultaneously hemizygous
or homozygous for vermilion have white eyes. Flies simultaneously
homozygous for both the brown and scarlet mutations also have white
eyes. Flies that are wildtype at all 3 loci have wildtype eye
color. Flies that are homozygous or hemizygous for the recessive
mutant at only one...
The results for the F2 progeny are shown for a F1 cross using the two X-linked...
The results for the F2 progeny are shown for a F1 cross using
the two X-linked markers:
w+ and m+.
As shown in the figure, the F1 cross is between the following
two parents:
- a phenotypically wild-type (red eye, full wing), heterozygous
female: w+m+/wm
- a double mutant male (white eye, miniature wing):
wm/Y
Answer the following questions:
1) In the F1 cross, can you infer the genotype for the phenotype
in the female? Why or why not?
2)...
Suppose that a geneticist discovers a new mutation in Drosophila melanogaster that causes the flies to...
Suppose that a geneticist discovers a new mutation in Drosophila melanogaster that causes the flies to shake and quiver. She calls this mutation quiver, qu, and determines that it is due to an autosomal recessive gene. She wants to determine whether the gene encoding quiver is linked to the recessive gene for vestigial wings, vg. She crosses a fly homozygous for quiver and vestigial traits with a fly homozygous for the wild-type traits, and then uses the resulting F1 females...
In Drosophila, the X-linked recessive mutation vermilion (XV) causes bright red eyes, in contrast to the...
In Drosophila, the X-linked recessive mutation vermilion (XV) causes bright red eyes, in contrast to the brick-red eyes of wild type (X+). Part A separate autosomal recessive mutation (br), causes the eyes to be brown. Predict the F1 results of the following cross: normal females x white males. (Assume that the parents are homozygous.) Flies carrying both mutations lose all pigmentation and are white-eyed. Label the diagram by dragging the labels to the appropriate targets. Note: not all labels will...
A mutation in the Drosophila bristle gene (fb) (which is X-chromosome linked) causes a recessive forked...
A mutation in the Drosophila bristle gene (fb) (which is X-chromosome linked) causes a recessive forked bristle phenotype (rather than the normal type of bristle). Another mutation in Drosophila autosomal body color gene (BR) causes a recessive brown color body (rather than the normal black body). A geneticist carried out the following cross: X+ / Y ; BR/br x X+/ Xfb ; BR/br If total of 240 F1 progeny were obtained, the “expected” numbers are: normal bristle male progeny -...
Practice 7.1. Cross a female fly with the eyeless mutation (a) for eye shape but normal bristle (b+) to a male fly with wild type eye shape (a+) with shaven bristles (b). Both of these genes are located on Mate a female fly with mutant traits of a black body (c), bristle (b), and wing veins (v) to a wild- type male (normal body color (c+), bristle (b+), and wing size (v+)]. These three alleles are located on chromosome II...
717 pts). In Drosophila, two recessive mutations delta vein (d) and rough eye (r) both map to chromosome 3 and are known to be 20 m.u. apart. Another recessive mutation, garnet eye color (a) has been mapped to the X chromosome. A delta veined, rough and garnet eyed- female was crossed to a wild-type male. The resulting fī females are testcrossed to delta-veined, rough and, garnet-eyed males. dng larg & ORG/ A. (6pts) Write the genotype of the Fı female...
2. The allele b gives Drosophila flies a black body, and bt gives brown, the wild-type phenotype. The allele wx of a separate gene gives waxy wings, and wx+ gives nonwaxy, the wild-type phenotype. The allele cn of a third gene gives cinnabar eyes, and cn* gives red, the wild-type phenotype. A female heterozygous for these three genes is testcrossed, and 1000 progeny are classified as follows: 5 wild type, 6 black waxy cinnabar, 69 waxy cinnabar, 67 black, 382...
Mapping genes with recombination frequencies in Drosophila 1. Suppose you know of three linked loci on the Drosophila X chromosome (a, b, and c). Assume that you are starting out with true-breeding stocks that show all three recessive traits and true-breeding stocks that show all three dominant traits. A. If you wanted to do a 3-point test cross to map the three loci, how would you set up the cross? What genotypes do you use for males and females in...
In Drosophila, the autosomal recessive brown eye color mutation
(b) displays interactions with both the X-linked recessive
vermilion mutation (v) and the autosomal recessive scarlet (s)
mutation. Flies homozygous for brown and simultaneously hemizygous
or homozygous for vermilion have white eyes. Flies simultaneously
homozygous for both the brown and scarlet mutations also have white
eyes. Flies that are wildtype at all 3 loci have wildtype eye
color. Flies that are homozygous or hemizygous for the recessive
mutant at only one...
The results for the F2 progeny are shown for a F1 cross using
the two X-linked markers:
w+ and m+.
As shown in the figure, the F1 cross is between the following
two parents:
- a phenotypically wild-type (red eye, full wing), heterozygous
female: w+m+/wm
- a double mutant male (white eye, miniature wing):
wm/Y
Answer the following questions:
1) In the F1 cross, can you infer the genotype for the phenotype
in the female? Why or why not?
2)...
Suppose that a geneticist discovers a new mutation in Drosophila melanogaster that causes the flies to shake and quiver. She calls this mutation quiver, qu, and determines that it is due to an autosomal recessive gene. She wants to determine whether the gene encoding quiver is linked to the recessive gene for vestigial wings, vg. She crosses a fly homozygous for quiver and vestigial traits with a fly homozygous for the wild-type traits, and then uses the resulting F1 females...
In Drosophila, the X-linked recessive mutation vermilion (XV) causes bright red eyes, in contrast to the brick-red eyes of wild type (X+). Part A separate autosomal recessive mutation (br), causes the eyes to be brown. Predict the F1 results of the following cross: normal females x white males. (Assume that the parents are homozygous.) Flies carrying both mutations lose all pigmentation and are white-eyed. Label the diagram by dragging the labels to the appropriate targets. Note: not all labels will...
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