What is the Nernst (equilibrium) potential of a monovalent cation (+ valence) at 37oC given the...
What is the Nernst (equilibrium) potential of a monovalent cation (+ valence) at 37oC given the intracellular ion concentration is 10 mM and the extracellular ion concentration is 80 mM?
Homework Answers
According to Nernst equation, nernst potential can be derived by,
Veq = (RT/zF)* ln(Xout/Xin)
Where,
Veq - Nernst potential
R - Universal gasconstant - 8.314 J/K/mol
T- Temperature in Kelvin (K= 0C+ 373.15) = Here 37+373.15 = 410.15K
z- Valancy of ion - for a monovalant cation z = +1
F - Faraday gas constant = 96485 C/mol
By applying into the equation, we get,
( (8.314 * 410.15) /(1 * 96485) ) / ln (80/10)
= 0.0353 * ln(8)
= 0.0353 * 2.079
= 0.0734V or 73.4mV
Therefore, the nerst potential for the given values are 73.4mV.
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