Which drug candidates are most effective at docking with COX1 and COX2 respectively? COX1: flurbiprofen, COX2:...

Question

Question

Which drug candidates are most effective at docking with COX1 and COX2 respectively?

COX1: flurbiprofen, COX2: celecobix

COX1: nimesulide, COX2: flurbiprofen

COX1: flurbiprofen, COX2: salicylic acid

COX1: celecobix, COX2: salicylic acid

Answer 1

Answer #1

Celecoxib is a class of COX2 inhibiting nonsteroidal anti-inflammatory drug that is generally used to treat pain and inflammation.

It is a reversible inhibitor of cyclooxygenase-2 having anti-inflammatory, antipyretic and analgesic effect.

Flurbiprofen is a class of COX1 inhibiting nonsteroidal anti-inflammatory drug used as anti-mitotic and dental pain drug.

It can also inhibit COX-2

Hence 1st option is correct.

Answer 2

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