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QUESTION 2 non-carbohydrate precursors for gluconeogenesis are lactate. glycerol, and amino acids. Your textbook (T ymoczkode
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QUESTION 2 non-carbohydrate precursors for gluconeogenesis are lactate. glycerol, and amino acids. Your textbook (T ymoczkode Fig 17.1: Bergße Fig 1624) shows where these metabolites enter into the gluconeogenic pathway. Evaluate the energetic cost to make one glucose molecule from one 1.5 ATP equlvalents per cytoplasmic molecule of each precursor in terms of ATP equivalents (total ATP and GTP directly consumed plus NADH oxidized). ATP equivalents consumed to make 1 glucose Aspartate (entry at axaloac Ghycerol (entry at DHAP) Lactate (entry at pyruvate)
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vate 2ATP 6 ATP enolpyauv 2 ATP 2ADP 2NAP+ 2 DHAP O ATP i ¢glucose

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