Postlab Assignment for Minilab 34 “Preparation of Aldol Condensation Produ...
Postlab Assignment for Minilab 34 “Preparation of Aldol Condensation Products”
1. Explain why benzaldehyde is expected to be the most reactive aldehyde among the three aldehydes used in this experiment. (used benzaldehyde, 4-methylbenzaldehyde, and 4-methoxybenzaldehyde)
2. What is the role of aqueous NaOH used in the experiment you carried out?
3. How would you change the procedures in this experiment if you wished to synthesize benzalacetophenone (C6H5CH=CHCOC6H5). Just indicate the two main organic starting materials.
4. Write a mechanism for the Aldol Condensation reaction involving cyclohexanone and benzaldehyde. In this mechanism, only show Aldol condensation between cyclohexanone and onemolecule of benzaldehyde.
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Postlab Assignment for Minilab 34 “Preparation of Aldol Condensation Produ...
What are the possible aldol condensation products and structures of the products from this list of...
What are the possible aldol condensation products and structures of
the products from this list of ketones and aldehydes?
Possible ketones: acetone, cyclopentanone, cyclohexanone, and 4-methylcyclohexanone, Possible aldehydes: benzaldehyde, 4-methylbenzaldehyde, 4-anisaldehyde, and trans cinnamaldehyde.
This experiment was based on Aldol-dehydration reaction using unknown aldehydes and ketones. We carried out an...
This experiment was based on Aldol-dehydration reaction using
unknown aldehydes and ketones. We carried out an aldol condensation
between an unknown aldehyde and an unknown ketone. Here are the
list of possible unknown aldehydes and ketones that were used.
Here is the NMR of the final product. Please predict the
structure given the melting point is 163 degrees Celsius.
The analysis of the 1H NMR spectrum should include a detailed
assignment of each of the NMR resonances to the protons...
Aldol-dehydration reaction Please draw all 25 products formed from the reaction of the below ketones and...
Aldol-dehydration reaction Please draw all 25
products formed from the reaction of the below ketones and
aldehydes. Mechanism is not necessary.
acetone cyclopentanone cyclohexanone 4-methylcyclohexanone cycloheptanone H H CHO H CHO Meo benzaldehyde 4-methylbenzaldehyde (p-tolualdehyde) 4-methoxybenzaldehyde p-anisaldehyde E-3-phenylpropenal (cinnamaldehyde) 2-furaldehyde (furfural) Ketone Aldehyde acetone cyclopentanone cyclohexanone 4-Me-cyclohexanone cyloheptanone benzaldehyde 113 °C 189-190 °C 118-119 °C 98-99 °C 106-107°C tolualdehyde 175 °C 233-235 °C 170 °C 134-136 °C 131-133°C anisaldehyde 129-130 °C 212-214°C 160-162 °C 136 °C 128-129°C cinnamaldehyde 144-145 °C...
Experimental Outline In its simplest form, the aldol condensation is a self-addition involving tw...
Organic Chemistry 2
Experimental Outline In its simplest form, the aldol condensation is a self-addition involving two molecules of the same aldehyde or ketone, in the presence of a base, and results in the formation of a new carbon-carbon bond joining the carbonyl carbon of one molecule to the a-position of the second. In many cases - if the reaction conditions aren't sufficiently mild - the initially formed aldol product reacts further in an elimination reaction to give what is...
Preparation of and alpha, beta-unsaturated ketone via Michael and Aldol Condensation
Preparation of and alpha, beta-unsaturated ketone via Michael and Aldol Condensation: 6-ethoxycarbonyl-3,5-diphenyl-2-cyclohexanone.Draw a mechanism for each of the three steps in the preparation of 6-ethoxycarbonyl-3,5-diphenyl-2-cyclohexenone. You may assume that NaOH functions as a base andethanol serves as a proton source
Lab 8: Preparation of an a B-Unsaturated Ketone via Michael and Aldol Condensation Reactions of a...
please write a balanced eqaution for this reaction
We were unable to transcribe this imageLab 8: Preparation of an a B-Unsaturated Ketone via Michael and Aldol Condensation Reactions of an a, B-Unsaturated Ketone via Michael and Aldol Condensation Reactions Finally, the aldol intermediate is dehydrated to form the final product, 6-ethoxycarbonyl-3,5-diphenyl-2-cyclohexenone. The a Bunsaturated ketone that is formed is very stable because of the conjugation of the double bond with both the carbonyl group and a phenyl group. CH2Et-O CH...
Determine the theoretical and percent yield for this lab Wednerdouy 13 CH 4521-8: Crossed Aldol Condensation:...
Determine the theoretical and percent yield for this lab
Wednerdouy 13 CH 4521-8: Crossed Aldol Condensation: Synthesls of trans-p-anisalacetophenone Ketones that contain an a-hydrogen (a hydrogen on the C right next door to the carbonyl group) can be tabilized via keto-enol tautomerization, or through the loss of the a-hydrogen to form an enolate anion. enolate anion Enolate ions actas nudbophiles and are considerable more reactive than tois. The enolate on i the subject of today's experiment. The formation of an...
Chemistry 326 Laboratory Manual obowy zawabnya CH, HycoF OCH Pre-Lab Assignment: Complete BEFORE Lab! (5 pts)...
Chemistry 326 Laboratory Manual obowy zawabnya CH, HycoF OCH Pre-Lab Assignment: Complete BEFORE Lab! (5 pts) 1. Draw the ketones and aldehydes necessary to synthesize ALL compounds A-F via double Aldol condensation. 2. Determine the moles of acetone and the moles of benzaldehyde used in the sample procedure below. NOTE: you will need to find the density of acetone and benzaldehyde to do this exercise. 3. Using the same number of moles you calculated above, determine the VOLUME of each...
Lab : Aldol Condensation Purpose. In this lab you will conduct the Aldol condensation reaction under solid-state...
Lab : Aldol Condensation Purpose. In this lab you will conduct the Aldol condensation reaction under solid-state reaction conditions that will involve grinding reactants in the solid phase. You must read ahead and learn about this reaction and the chemical mechanism for the Aldol condensation. There are two possible products which are the initial Aldol or subsequent elimination product. You will need to isolate and purify your reaction product. You will use your melting point, IR, 1H and 13C NMR spectra to...
QUESTION 33 2 points ($18.7) What is the product of the following crossed aldol condensation? (Complete...
QUESTION 33 2 points ($18.7) What is the product of the following crossed aldol condensation? (Complete aldol reactions using two different aldehydes or ketones.) Reagents: acetyl aldehyde + p-chlorobenzaldehyde (no alpha hydrogen) + NaOH a strong base + H20 and heat.) HOA o oo QUESTION 34 2 points (518.7) Which compound, in a reaction with the ketone below, would produce the fewest side products? (Identify which aldol reactions will proceed in high yield). Reagents: starting material acetone + (1) NaOH...
What are the possible aldol condensation products and structures of
the products from this list of ketones and aldehydes?
Possible ketones: acetone, cyclopentanone, cyclohexanone, and 4-methylcyclohexanone, Possible aldehydes: benzaldehyde, 4-methylbenzaldehyde, 4-anisaldehyde, and trans cinnamaldehyde.
This experiment was based on Aldol-dehydration reaction using
unknown aldehydes and ketones. We carried out an aldol condensation
between an unknown aldehyde and an unknown ketone. Here are the
list of possible unknown aldehydes and ketones that were used.
Here is the NMR of the final product. Please predict the
structure given the melting point is 163 degrees Celsius.
The analysis of the 1H NMR spectrum should include a detailed
assignment of each of the NMR resonances to the protons...
Aldol-dehydration reaction Please draw all 25
products formed from the reaction of the below ketones and
aldehydes. Mechanism is not necessary.
acetone cyclopentanone cyclohexanone 4-methylcyclohexanone cycloheptanone H H CHO H CHO Meo benzaldehyde 4-methylbenzaldehyde (p-tolualdehyde) 4-methoxybenzaldehyde p-anisaldehyde E-3-phenylpropenal (cinnamaldehyde) 2-furaldehyde (furfural) Ketone Aldehyde acetone cyclopentanone cyclohexanone 4-Me-cyclohexanone cyloheptanone benzaldehyde 113 °C 189-190 °C 118-119 °C 98-99 °C 106-107°C tolualdehyde 175 °C 233-235 °C 170 °C 134-136 °C 131-133°C anisaldehyde 129-130 °C 212-214°C 160-162 °C 136 °C 128-129°C cinnamaldehyde 144-145 °C...
Organic Chemistry 2
Experimental Outline In its simplest form, the aldol condensation is a self-addition involving two molecules of the same aldehyde or ketone, in the presence of a base, and results in the formation of a new carbon-carbon bond joining the carbonyl carbon of one molecule to the a-position of the second. In many cases - if the reaction conditions aren't sufficiently mild - the initially formed aldol product reacts further in an elimination reaction to give what is...
please write a balanced eqaution for this reaction
We were unable to transcribe this imageLab 8: Preparation of an a B-Unsaturated Ketone via Michael and Aldol Condensation Reactions of an a, B-Unsaturated Ketone via Michael and Aldol Condensation Reactions Finally, the aldol intermediate is dehydrated to form the final product, 6-ethoxycarbonyl-3,5-diphenyl-2-cyclohexenone. The a Bunsaturated ketone that is formed is very stable because of the conjugation of the double bond with both the carbonyl group and a phenyl group. CH2Et-O CH...
Determine the theoretical and percent yield for this lab
Wednerdouy 13 CH 4521-8: Crossed Aldol Condensation: Synthesls of trans-p-anisalacetophenone Ketones that contain an a-hydrogen (a hydrogen on the C right next door to the carbonyl group) can be tabilized via keto-enol tautomerization, or through the loss of the a-hydrogen to form an enolate anion. enolate anion Enolate ions actas nudbophiles and are considerable more reactive than tois. The enolate on i the subject of today's experiment. The formation of an...
Chemistry 326 Laboratory Manual obowy zawabnya CH, HycoF OCH Pre-Lab Assignment: Complete BEFORE Lab! (5 pts) 1. Draw the ketones and aldehydes necessary to synthesize ALL compounds A-F via double Aldol condensation. 2. Determine the moles of acetone and the moles of benzaldehyde used in the sample procedure below. NOTE: you will need to find the density of acetone and benzaldehyde to do this exercise. 3. Using the same number of moles you calculated above, determine the VOLUME of each...
QUESTION 33 2 points ($18.7) What is the product of the following crossed aldol condensation? (Complete aldol reactions using two different aldehydes or ketones.) Reagents: acetyl aldehyde + p-chlorobenzaldehyde (no alpha hydrogen) + NaOH a strong base + H20 and heat.) HOA o oo QUESTION 34 2 points (518.7) Which compound, in a reaction with the ketone below, would produce the fewest side products? (Identify which aldol reactions will proceed in high yield). Reagents: starting material acetone + (1) NaOH...
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