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what is the type of metabolism in the plasmodium parasite that causes malaria?

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Type of metabolism in the plasmodium parasite that causes Malaria: Hemoglobin metabolism

  • Hemoglobin metabolism in Plasmodium falciparum (malaria parasite) occurs in the digestive vacuole. Heme is utilized in the mitochondrial electron transport chain and is therefore an essential molecule for the growth of parasite and sexual replication during the intraerythrocytic stage.
  • The parasites also possess heme de novo biosynthetic pathway. The food vacuole of the parasite contains protease enzymes that are involved in the degradation of hemoglobin.
  • Hemoglobin biosynthesis pathway is an important and potential target for the development of effective antimalarial drugs.
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