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How can a dominant lethal mutation (such as that for Rest Syndrome) be transmitted to future generations? - Rett syndrome caused by mutations in the gene that encodes MeCP2 and is X-linked

How can a dominant lethal mutation (such as that for Rest Syndrome) be transmitted to future generations? - Rett syndrome caused by mutations in the gene that encodes MeCP2 and is X-linked

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Answer. As we know females have two X chromosome and male has one X chromosome, so Rett syndrome is lethal for boys when it has mutated X chromosome while female can have this syndrome which relates to slower development of body and brain.

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