LYSOGENIC CYCLE
1. The prokaryotic cell is shown with its DNA which is shown in green.
2. The bacteriophage attaches and releases its DNA, shown in red, into the prokaryotic cell.
3. The phage DNA then moves through the cell to the host’s DNA.
4. The phage DNA integrates itself into the host cell's DNA, creating prophage.
5. The prophage then remains dormant until the host cell divides.
6. After the host cell has duplicated, the phage DNA in the daughter cells activate, and the phage DNA begins to express itself. Some of the cells containing the prophage go on to create new phages which will move on to infect other cells.
LYTIC CYCLE
In the lytic cycle, the viral DNA exists as a separate free-floating molecule within the bacterial cell, and replicates separately from the host bacterial DNA, whereas in the lysogenic cycle, the viral DNA is located within the host DNA. This is the key difference between the lytic and lysogenic (bacteria)phage cycles. However, in both cases, the virus/phage replicates using the host DNA machinery.
The lytic cycle, which is also commonly referred to as the "reproductive cycle" of the bacteriophage, is a six-stage cycle. The six stages are: attachment, penetration, transcription, biosynthesis, maturation, and lysis.
IMPLICATION OF LYSOGENY IN HUMAN HEALTH
The gut microbiota consists of various microorganisms including bacteria (bacterial microbiota), bacteriophages and eukaryotic viruses (virobiota) and other microorganisms (fungi and archaea). Bacteriophages—bacterial viruses that attack specific bacteria—have been found in both animal and human organisms (oral, gastrointestinal and respiratory tracts, urine and serum) . Phages constitute an alternative to the use of antibiotics and are particularly applicable in the treatment of antibiotic-resistant bacterial infections . Bacteriophages replicate by two alternative cycles: lytic and lysogenic life cycles . In the lytic cycle phages infect bacteria leading to the production of new phage particles and degradation (lysis) of bacteria. A single phage particle adsorbs to a bacterial cell, then multiplies within. Progeny phages lyse the bacterial cell and release approximately 50–100 phage particles in one growth cycle . During the lysogenic cycle the genetic material of the phage may integrate into the bacterial genome, a process which does not lead to lysis of the bacteria . In recent years there has been observed growing interest in the human gut microbiota and its effects on health and disease of humans . It is suggested that gut microbiota may have an influence on the development of metabolic inflammation in obesity and diabetes . Detection of phages may be performed by traditional bacterial lysis methods . Bacteriophage abundance, diversity and morphology are investigated in transmission electron microscopy . In recent years, researchers have begun to characterize the diversity of viruses using metagenomic methods . A huge number of phages in the intestine have been investigated using electron microscopy, and their diversity has been investigated in metagenomic studies .
6. In class we discussed the lytic and lysogenic cycles in phage. Draw out the cycles. What are some of the implications of lysogeny to human health? 6. In class we discussed the lytic and l...
distinguish between the lytic, lysogenic and slow-release viral cycles. What are the relative advantages and disadvantages of the slow-release strategy, comparee with the strategy of a temperate phage, which alternates between lysis and lysogeny?
(3) In our class on Health & Human services, we will look at the state of poverty in the states, and 5 of the major safety net programs that are intended to provide assistance to those in need. What programs should be revised to meet the gaps, as we have identified in the safety net programs?
A. What are some of the key aspects of each of the levels of awareness we discussed in class-be specific as to what occurs within each of the levels of awareness Be as specific as possible noting what occurs in each of these levels; one or two lines is not sufficient. 1. Higher Level 2 Lower Level 3 Subconscious Level 5. Altered States of Consciousness OR B Both Pavlov's and Skinner's theories of learning f differences in how each explains...
What are two common forms of human errors? Describe where each one results from. Describe their differences. How do we prevent these errors from occurring using the concepts discussed in class
Given what we have discussed during this week, apply what you know to some issues that relate to health insurance markets since passage of the Affordable Care Act and expansion of some managed care options in those markets. What happens to actuarially fair premiums? What about the loading charge? Do consumer preferences for risk change? How? What about employers and employee plans? Also, think about the 80% Medical Loss Ratio limitation. Does that impact the market and if so, how?
In class, we discussed a scenario involving 802.11, VPN, and ssh identifying three distinct 6. points of encryption. For each of these, describe what compromises, if any, would be possible by removing that encryption. The point of this question is to determine to what degree you can incrementally move to a better architecture by making stepwise changes to the existing structure. In class, we discussed a scenario involving 802.11, VPN, and ssh identifying three distinct 6. points of encryption. For...
this question on the pic In class this week we discussed some of the principles of point selection, including the role of the practitioner's intuition and the image that you hold in your mind for the treatment. What do you see as the most important principles to keep in mind when making acupuncture point selections? Besides learning the actions and indications of channels and points, what sorts of skills and knowledge do you hope to cultivate to help you with...
______ 6. In class, we discussed the “winner’s curse” as it relates to purchases of stock in an IPO by small “retail” investors. Assume you are one of these small retail investors and you place orders to purchase 1,000 shares of stock in two different IPOs. According to the winner’s curse, on which of these two IPO purchases would you expect to earn the highest rate of return? A. An IPO in which you receive full allocation on your order...
In class we discussed the concept of wage differentials. Historically, a correlation has existed between educational attainment and income level. Acquiring more education (human capital) has always been promoted as a means of escaping poverty. Unfortunately, due to rising college costs, students have taken on unprecedented levels of student loan debt. For this paper, you will research (with a minimum of three additional resources) the "student loan bubble" and proposed solutions to assist the impacted economic actors. The paper should...
3. (8 points) Using the implementation of binary search tree operations we discussed in class, draw the trees that result from the following operations: (a) Inserting 142, 400, 205, 127, 100, 320, 160, 141, and 110 into an initially-empty tree (in that order). (b) Deleting 142 from the tree you drew for part (a). 4. (8 points) Draw the unique binary tree that has a preorder traversal of 4, 1, 6, 3, 7, 5, 9, 2, 8 and an inorder...