Answer at least 7 of the following questions: a) Describe the weak intermolecular forces (charge-charge, H-bond, van de...
a) Describe the weak intermolecular forces (charge-charge, H-bond, van der Waals, & Hydrophobic force etc). b) Describe the structural properties of the peptide bond, a-helix, B-turn, B -sheet and random coil. c) Describe the structural hierarchy of a protein (1°, 2°, 3° & 4) using examples of globular proteins d) Describe how BME or DTT affects disulfide linkages connecting dimeric and multimeric proteins e) Describe Kd, Km and Vmax of an enzyme and saturating conditions. f) Describe the mechanisms of inhibition and characterize (what does the lineweaver-burke plot look like g) Describe the role of CO2, pH, 2,3-BPG, O2 and in HB fxn h) Describe the general modes of catalysis. i) Describe the difference between DG' and DG'°. ) Identify/describe functional groups with "good" group transfer potential. k) Describe why and when pyruvate undergoes conversion to either ethanol or lactate. I) When and where does gluconeogenesis occur? m) Describe coupling of the electron transport chain and ATP synthase.
a) Describe the weak intermolecular forces (charge-charge, H-bond, van der Waals, & Hydrophobic force etc). b) Describe the structural properties of the peptide bond, a-helix, B-turn, B -sheet and random coil. c) Describe the structural hierarchy of a protein (1°, 2°, 3° & 4) using examples of globular proteins d) Describe how BME or DTT affects disulfide linkages connecting dimeric and multimeric proteins e) Describe Kd, Km and Vmax of an enzyme and saturating conditions. f) Describe the mechanisms of inhibition and characterize (what does the lineweaver-burke plot look like g) Describe the role of CO2, pH, 2,3-BPG, O2 and in HB fxn h) Describe the general modes of catalysis. i) Describe the difference between DG' and DG'°. ) Identify/describe functional groups with "good" group transfer potential. k) Describe why and when pyruvate undergoes conversion to either ethanol or lactate. I) When and where does gluconeogenesis occur? m) Describe coupling of the electron transport chain and ATP synthase.