1. Give the major product of the following reactions, write N.R. if no reaction happens. Indicate the stereochemistry if necessary:
1. Give the major product of the following reactions, write N.R. if no reaction happens. Indicate the stereochemistry if...
1. Give the major product of the following reactions, write N.R. if no reaction happens. Indicate the stereochemistry if necessary: i 1. NaBH, MOH 2. H, H2O 3. conc. H2SO4, heat 1. LiAlH4, THE 2. H, H2O 3. MSCI, Pyr, 0 °C 1. SOCI, EIN -D 2. LAIH, ether 1. Li, hexane 2. i . THE 3. acidic work-up Jone's reagent ОН OH 1. PBT 2. NaCN, THE PH conc. H2SO4 NaCl 0°C conc. HBO OH heat
1. Give the major product of the following reactions, write N.R.
if no reaction happens. Indicate the stereochemistry if
necessary:
1. Give the major product of the following reactions, write N.R. if no reaction happens. Indicate the stereochemistry if necessary: CHCl3 KOC(CH3)3, (CH3)3COH 1. conc. HBr, heat 2. KOBU, HOBU ✓ 1. NaoMe, MeOH 2. BrCN 1. 1 eq. BH3, THE 2. H2O2, NaOH, H20 3. Hg(OAc)2, MeOH 4. NaBH4, NaOH, H20
1. Give the major product of the following reactions, write N.R.
if no reaction happens. Indicate the stereochemistry if
necessary:
h. 1. Cl2, H2O 2. KOtBu 1. NaOH, H20 2. PCC НО i. 1. ICH2Znl, Et2O 2. MSCI, pyr 3. LDA ОН j. 1. HВг, "BuOOH, hv 2. NaCN, DMF
1. Give the major product of the following reactions, write N.R.
if no reaction happens. Indicate the stereochemistry if
necessary:
1. conc. HCI 2. LDA, THE 3. O3, CH3OH 4. (CH3)2S N2 hv 1. Hg(OAC)2, THE 2. NaBH4, NaOH, H20 Y-OH (Hint: product has a bicyclic ring)
1. Give the major product of the following reactions, write NR. if no reaction happens. Indicate the stereochemistry if necessary CHCI KOC(CH3). (CH),COH 1. conc. HBr, heat 2. KOBU, HOBU 1. NaOM, MOH CI 2. BICN 1. 1 eq. BH3. THE 2. H2O2, NaOH, H2O 3. Hg(OAC), MeOH 4. NaBH4, NaOH, H2O 1. conc. HCI 2. LDA, THF 3. O. CH,OH 4.(CH), 1. Hg(OAC), THE 2. NaBH, NaOH, H2O > OH (Hint: product has a bicyclic ring)
Give the major product(s) (indicating stereochemistry where
appropriate) of each of the following reactions.
он a) 2. 3. H (any strong acid) 1. HBr(1 equiv) MgBr, then 20 2. Mg then H20 OH c) 2. MeMgBr, then H20 3. PBr3, pyridine 4. NaCN 1. HBr (2 equiv) 2. NaNH2 (2 equiv) d) 1. BH3 2. HOOH, NaOH 3. TsCI, pyridine 4. NaSH
Unit 3 Hinw '3 SNİSNDELE2 1. Give the major product(s) for the following reactions. Indicate the mec reaction occurs, write "no reaction. s) in operation. If no KOC(CH) (CH COH b. H3C NaNH2 NHy Nal H3C H2CH-CH3 CH,COCH CH OH CH3 2. Give the mechanism of each of the following reactions. NaCN CH CH CHCN NaBr a. CH,CH,CH Br acetone HSCH,CH (CH) CSCH,CH3 HBr Cl + NaCI + CH OH NaOCH CH3OH Br CH OH CH3
Give the major organic product(s) of the following reactions or
sequences of reactions. Show the stereochemistry and/or isotope
position clearly where it is relevant. If you think that the
reaction would not occur, write as "NR" or "No Reaction."
A) 1) NaCN A. 2)H30+ heat OH B) 1) PCC/ CH CL 2) (CHỊ) CHNH2 ?
1. Provide the products of the following reactions. Write N.R. if there is no reaction happens. NH2 Nal Acetone CH COONa - foto 57 NaOM NaSH DBU EtOH NaCN EtONa Me- Br -Me
1. Predict the product (s) (or no reaction) and reagent(s). (31 pts; no partial point) 1. TsCI, pyridine OH 2. SNa b. OH NaH C. HBr 2 eq, 0 °C d. ОН H2SO4 heat CH3 HBr Он heat f. но 1. PBr3, EtzO 2. NaCN OH NaH OTs h. Он HBr 0°C CH3 H2SO4 heat Он