Question

1.Some sugar substitutes are made from derivatives of sucrose. SucraloseTM is a sweetener found in soft drinks and low-calorie foods such as yogurt. The structure of Sucralose is shown below in both 2D and 3D representations. Highlight the chirality centers...

2.Highlight, by clicking on, the asymmetric carbons (if any) in each structure.

Answer 1

Concepts and reason

Asymmetric carbon (chiral centre) can be identified, when the carbon atom is bonded with four different groups or atoms. Represent the asymmetric carbon with the green colour.

Fundamentals

Chirality centre: An atom (usually carbon) which is bonded to four different atoms or groups is known as chiral centre. In general, it is represented with an asterisk (*).

An asymmetric carbon atom is carbon atom that is attached to four different types of atoms or groups. This leads to a chiral centre.

A stereo enter is a point in a molecule bearing groups, such that it produces two stereoisomers on interchanging any two groups. A chiral carbon may also be a stereo enter.

If the two high priority groups are on the same side of the double bond, then it is known as Z isomer.

If the two high priority groups are on the opposite side of the double bond then it is known as E isomer.

(1)

The chiral carbons are labelled in 2D structure of sucralose as follows:

The chiral centres in 3D structure are drawn as follows:

(2)

The chiral and stereo centres in this structure are as follows:

The chiral and stereo centres in this structure are represented as follows:

Ans:

The nine chiral centres (represented with the green colour) are as follows: