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Case Study: The 5 year old son of a Liberian exchange student was hospitalized because of low grade fever, pain, severe...

Case Study: The 5 year old son of a Liberian exchange student was hospitalized because of low grade fever, pain, severe diarrhea, abdominal distention, and splenomegaly. He also has swelling of his lower extremities. On admission, the physician ordered a CBC. A blood test indicated a decreased red blood cell and platelet count with extensive anisocytosis and poikiocytosis. He has had two similar episodes in the past, but did not seek medical treatment. The episodes resolved without any intervention. Question: Based on the clinical and laboratory presentation of this case, what is your final diagnosis? Why?

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Answer #1

1 The most probable diagnosis will be Thrombotic Thrombocytopenic Purpura,as it is characterized by fever,diarrhea and splenomegaly.Examination of peripheral blood smear also shows anisocytosis.

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