Question

Case Study: The 5 year old son of a Liberian exchange student was hospitalized because of low grade fever, pain, severe diarrhea, abdominal distention, and splenomegaly. He also has swelling of his lower extremities. On admission, the physician ordered a CBC. A blood test indicated a decreased red blood cell and platelet count with extensive anisocytosis and poikiocytosis. He has had two similar episodes in the past, but did not seek medical treatment. The episodes resolved without any intervention. Question: Relate the pathophysiologic changes to the manifestations and lab results.

Answer 1

Thrombocytopenic purpura,which is also called immune thrombocytopenia affects children and adults.Children often develop the condition after a viral infection and usually recover fully without treatment.it is a blood coagulation disorder which result in microscopic clots with low platelet counts..Many people experience influenza -like or diarrheal diseases before developing a ThromboticThrombocytopenic Purpura.There are five constellation signs and it includes fever,thrombocytopenia,reduced kidney function and haemolytic enemia.The main characteristic of the disease is due to the formation of clots which could lead to haemolytic anaemia and thrombocytopenia.Patients may exhibit neurological symptoms,kidney impairement abd gastrointestinal symptoms.