Protic solvents contain hydrogen bonds, thus O-H or N-H bonds. Examples are water, ethanol (alcohols in general), acids and primary or secondary amines (tertiary amine contains no N-H bond).
Aprotic solvents contain no hydrogen bonds, but it still needs to be polar for substitution or elimination reactions. Because the transition state is polar at least and possibly also the starting substance and/ or product, a nonpolar solvent like hexane won’t produce any reaction like this as the transition state isn’t stabilized. Examples of polar aprotic solvents are dimethylformimide (DMF), dimethylsulfuroxide (DMSO), ethylacetate and dichloromethane. (These molecules contain halides or oxygen to make it polar in general but no O-H or N-H bonds).
In Sn2 reactions (or E2), the nucleophile needs to react with the starting substance and this is the rate determining step. If the solvent is protic then it will stabilize the nucleophile so much that it basically won’t attack. Thus an aprotic solvent is needed, but remember that it still needs to be polar to stabilize the stransition state.
In Sn1 reactions (or E1), the rate determining step is forming the carbocation. It doesn’t matter if the nucleophile is stabilized by a protic solvent as the carbocation attracts the nucleophile enough to still make it attack (the carbocation has a formal charge while the starting substance is a bit polar at most, in general). Thus, it doesn’t matter if the solvent is protic or aprotic (but always polar).
3. (Solubility and equilibrium) Explain the following changes in equilibrium observed in experiments The explanation mu...
3. Solubility and equilibrium Explain the following changes in equilibrium observed in experiments The explanation must considera compounds and all of major factors. 15 pts) CHCI . CHON CH, OCH NI in water nearly 100% viold in hexane nearly 0% yield 4. Basicity and equilibrium) Complete the following reactions you must show more than one possible mechanisms before you choose the better one with a greatly detailed explanation. Then, explain the equilibrium and the explanation must be done in terms...
3. (Solubility and equilibrium) Explain the following changes in equilibrium observed in experiments. The explanation must consider all compounds and all of major factors. (5 pts) CH3CI + CH3ONa - сносн. Naci in water: nearly 100% yield in hexane: nearly 0% yield
3. (Solubility and equilibrium) Explain the following changes in equilibrium observedin experiments. The explanation must consider all compounds and all of major factors. (5 pts) NaCl CH3CI CH3ONA CH3ОCH3 + in water: nearly 100% yield in hexane: nearly 0 % yield
3. (Solubility and equilibrium) Explain the following changes in equilibrium observedin experiments. The explanation must consider all compounds and all of major factors. (5 pts) CH3CI + CH3ONa CH3OCH3 Naci in water: nearly 100% yield in hexane: nearly 0% yield
Q7. Consider the following equilibrium How will each of the following changes affect the equilibrium yield 1) Increasing Pressure of CO &CO. (g) + 6 H,O(l) -c.H.0. (s) + 6 0(g) ΔΕ1-28 16 kJ of CH O. Explain your reasoning. 2) Increasing temperature ) Removing CO 4) Decreasing the volume of the reaction vessel 5) Removing part of CH O, (s) 6) Adding a catalyst Q7. Consider the following equilibrium How will each of the following changes affect the equilibrium...
Consider the following S and your reaction to protect the effect of the changes given below on the rate of the reaction clearly state Whether it would react faster or slower or will be unaffected give a brief explanation why in each case 19. (9 pts.) Consider the following SN2 reaction to predict the effect of the changes given below on the rate of the reaction. (Clearly state whether it would react faster, slower or will be unaffected.) Give a...
questions: 2,3 & 4 1. Consider the following reaction: PCI (1) + Cu(a) PCIS (s) + BBkJ Equilibrium will shift ? (or How wil this affect the amoun no change) of CI, ? increase, decrease.no Change change) Increase the temperature Backwand Increase Add a catalyst unchanged unchange Increase the amount of chlorine Forward Decrease Add more PCI Do change No Change Increase the volume Balk ward increase Increase the pressure Forward I fecrease 2. What is equal at equilibrium? 3....
Experiments Dehydration of 2-methylcyclohexanol Questions 1. Please answer this question on notebook paper, not in the lab sometimes dimicult to read.) tebook (carbon copies are Consider the phosphoric acid-catalyzed dehydration of the following list of nine alcohols. Give the structure of each alcohol and that of the resultant alese. If a MIXTURE of alenes is anticipated. give both products and circle the major product (a) Cyclohexanol: (b) 1-methylcyclohexanol (c)2-methylcobecnold 3-methylcyclohexanol: (e) 4-methylcyclohexanol: (cyclopentanol (R) 3- canotth) 2-pentano: 0) 3-pentanol. 2....
2 pts) Which of the following reactions represents a standard formation reaction? a. 2C+02 → 2 CO ) (bH20 (2)→ H2 (0+:02 (8) c. C+%2020 → CO2) d. Hz (+ 1.026 → Hz () (Brief!) explanation of your choice: 3) (2.5 pts) Based on the heating curve for iron pictured below, what temperature is the melting point of iron? Heating Curve for Iron a. (1.0 pts) Label with a letter / the segment in which iron 3500 exists as a...