ORENCIA (abatacept), used to treat rheumatoid arthritis, is available in vials, each containing 250 mg of powdered drug,...
ORENCIA (abatacept), used to treat rheumatoid arthritis, is available in vials, each containing 250 mg of powdered drug, intended to be reconstituted to10 mL with sterile water for injection. The dose of abatacept depends on a patient's body weight: <60 kg, 500 mg; 60 to 100 kg, 750 mg; and >100 kg, 1 g. The contents of the appropriate number of vials are aseptically added to a 100-mL infusion bag or bottle of sodium chloride injection after the corresponding volume of sodium chloride injection has been removed. The concentration of abatacept in an infusion for a 200-lb. patient would be:
Homework Answers
200lb= 90.9 Kg
60-100kg weight, 750 mg is the dose
10 ml of the drug contains 250 mg
to add 750 mg,, how much ml of the medicine has to be added = 750× 10/250 = 30 ml
so to make the infusion of 100 ml, add 30 ml of Abatacept to 70 ml normal saline
the concentration is 750mg /100ml or 7.5 mg/ml
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ORENCIA (abatacept), used to treat rheumatoid arthritis, is available in vials, each containing 250 mg of powdered drug,...
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