Question

A patient order specifies: "Nitroglycerin 100 mg in 500 mL D5W. Infuse over 6 hours." If the administration set delivers 60 drops/mL, how many milligrams of drug is this patient receiving per hour? If 500-mL of an intravenous solution contains 0.3 g of a drug, at what flow rate, in milliliters per minute, should the solution be administered to provide 0.5 mg/min of drug? 500-mL of an intravenous solution contain 0.6% of drug in sodium chloride injection. At what flow rate, in milliliters/minute, should the infusion be administered to provide 150 mg of drug per hour? (10710) A patient is to receive an infusion of a drug at the rate of 54 mg/h for 2 hours. The drug is available in 300-ml vials containing 2 mg of drug per milliliter. If a 500-ml bag of sterile saline is used as the vehicle, how many milliliters of the drug solution should be added? Do not include units in your typed answer.

Answer 1

1Q).

The drug concentration is, 100 mg in 500 mL, or 1 mg per 5 mL.

The drop factor is, 60 drops per mL.

The duration of infusion is, 6 hours.

The volume delivered per an hour is, 500 mL / 6 hours = 83.33 mL /hr

The drug present in 83.3 mL is,

500 mL – 100 mg

83.3 mL – X

X (mg) = 100 mg * 83.3 mL / 500 mL

X (mg) = 16.6 or 17 mg/hr