Question

If 500-mL of an intravenous solution contains 0.3 g of a drug, at what flow rate, in milliliters per minute, should the solution be administered to provide 0.5 mg/min of drug? 500-mL of an intravenous solution contain 0.6% of drug in sodium chloride injection. At what flow rate, in milliliters/minute, should the infusion be administered to provide 150 mg of drug per hour? (10710) A patient is to receive an infusion of a drug at the rate of 54 mg/h for 2 hours. The drug is available in 300-ml vials containing 2 mg of drug per milliliter. If a 500-ml bag of sterile saline is used as the vehicle, how many milliliters of the drug solution should be added? Do not include units in your typed answer.

Answer 1

B. 500 ml contains 0.3 gram of drug means 300 mg of drug.

so 1 ml contains 0.6 mg of drug.

in order to achieve 0.5 mg per min, we need to administer 0.83 ml of drug as per the below calculation:

0.6/1 ml = 0.5/ X

X = 0.5/0.6 = 0.83 ml per min.

C. The answer is 0.416 ml per min.

500 ml contains 0.6 % of drug indicates that 1 ml contains 6 mg of drug.

1000 ml contains 6000 mg of drug

500 ml contain 3000 mg of drug.

in order to achieve 150 mg of drug per hour means 25 ml per hour is required.

25 ml/ 60 min shows 0.416 ml per min is the flow rate.

D. The stock drug solution is 2 mg per ml.

the desired flow rate is 54 mg per hour. So we need to add 27 ml for 1 hour infusion. So for 2 hour infusion we need to add 54 ml of drug solution from vial to 500 ml of saline