6. (4 pts.) Draw the two resonance structures of the enolate formed from the following reaction: 7. (4 pts) Draw th...
1. Unsymmetrical ethers can be made by the Williamson synthesis, in which an alkoxide ion reacts with an alkyl bromide. Draw the structure of the alkoxide and the alkyl bromide needed to produce 2-ethoxy-2-methylpropane (a.k.a t-butyl ethyl ether), shown below. Show charges where appropriate.HINT:The reaction involves an SN2 attack of the alkoxide on the alkyl bromide, displacing the bromide ion.R1O- + R2Br --------> R1-0-R2 + Br-What are the alkyl groups found in the ether? One alkyl group will come from...
) (6 pts) Carefully draw three resonance structures for the enolate ion formed when NaOEt is added to ethyl acetoacetate. NaOEt Page 2/7
3) Draw the structure of the enolate formed in the first reaction and then the mechanism of the Claisen reaction in the second reaction. (10 pts) LDA No mechanism in this step Mechanism starts here
1) Draw the structure of the enolate formed in the first reaction and then the mechanism of the addition in the second reaction. (8 pts) LDA No mechanism in this step Mechanism starts here
Draw both resonance structures of the enolate formed when each of the following ketones is treated with a strong base. Show mechanisms.
Draw a major resonance structure for the following enolate. Use curved arrows in both structures to show the delocalization of electron pairs. Include lone pairs of electrons, formal charges, and hydrogen atoms. Draw a major resonance structure for the following enolate. Use curved arrows in both structures to show the delocalization of electron pairs. Include lone pairs of electrons, formal charges, and hydrogen atoms.
2) Draw the structure of the enolate formed in the first reaction and then the mechanism of the Aldol reaction in the second reaction. There is an acid work up step at the very end to neutralize charges only. (10 pts) LDA No mechanism Mechanism starts here in this step
4. (2 pts) Consider the enolate forming reaction below. Provide the structure of the enolate anion formed in this reaction (only need to provide one resonance contributor). HiC o: H2C Нас pKa -20 pKa -33 Enolate oti (2 pts) Based on the information provided, do you expect the favored enolate to be the kinetic or thermodynamic enolate? Briefly explain.
3) Consider the following structure: a) (6 pts) Draw two additional resonance structures for the following compound. Show curved arrows to convert between the resonance structures. (You need to redraw the molecule below) b) (4 pts) Circle the major contributor above. Explain your choice 4) (5 pts) For the following compound draw in the lone pairs, indicate if each lone pair is localized or delocalized and identify what type of orbital each lone pair is in
In the boxes provided, draw the structures of the four intermediates and the enamine product formed in the following reaction. You don’t have to show the important resonance structures.I need to see the mechanism that leads to the intermediates and the product.