Question

NH3 CH2-C-COO 1 H + H2O + CH3-C-COO + NH4 N Tryptophanase Tryptophan Water Indole Pyruvate Ammonium

Propose a step by step reaction mechanism with an enzyme catalyst for the conversion of L-Trp to indole, pyruvate and ammonia.

NH3 CH2-C-COO 1 H + H2O + CH3-C-COO + NH4 N Tryptophanase Tryptophan Water Indole Pyruvate Ammonium

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NH3 HO H н. 0 -NH3 0 AZI Hни ZI NH3 NH4 ammonium O enol form indole Keto form

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