Question

Hey please help with the description of these drugs. This is a project on gastrointestinal pharmacology. Will rate

1. Which one would you prescribe? Which one works best for treating ulcers?

2. What is their potentiation effects if combined with other drugs such as cimetidine and ranitidine? Combining with anticholinergics to delay gastric emptying?

3. Key distinguishing features about these drugs

4. Anything else worth mentioning

thank you so much

Non-systemic : M1 receptor antagonists Pirenzepine (Gastrozepin) a. Antimuscarinic (lowers gastric motility, delays gastric emptying) b. Reduces gastric acid secretion and muscle spasms C. Promotes healing of peptic ulcers, gastric ulcers and duodenal ulcers Propantheline (Pro-Banthine) a. Antimuscarinic (lowers gastric motility, delays gastric emptying) b. Reduces gastric acid secretion and muscle spasms C. Promotes healing of peptic ulcers, gastri Mepenzolate a. Post-ganglionic parasympathetic inhibitor b. Decreases gastric acid and pepsin secretion c. Lowers contractions of the colon Side Effects: Dry mouth, blurred vision, constipation. Worsens symptoms of glaucoma.