Gabriel-melonic ester synthesis G 1-3 1. NaOH 2. isopropyl chloride 3. H3O* 4. acetyl chloride, Py -H H3O*/ BnOH H...
Select the most stable chair conformation for (1R,3S,5S)-1-chloro-3-isopropyl-5-methylcyclohexane. Select the most stable chair conformation for (1R,3S,5S)-1-chloro-3-isopropyl-5-methylcyclohexane Select the most stable chair conformation. CH(CH3)2 (1R,3S,5S)-1-chloro-3-isopropyl-5-methylcyclohexane Chair choices: CI CH CH3 CH3 (H3C)2HC CH(CH3)2 (H3C)2HC CH3 CH3 CH3 Cl CH(CH3)2 (H3C2HC (H3C)2HC
hohanol 3. 3,4-dimethyl-7-honanone is 10₂ 2) H₂O 3) NaOH 2 4) acetyl chloride a) OH b), H مٹہ (4 d) Y
the first two questions are asking to do acid-catalyzed mechanism. the last one is mutliple choice question yl-Fall 2019 SO. Draw the mechanism for the acid-catalyzed hydration of 3.3-dimethy the final product in the box below In words: protonation water gives a pro rearrangement to a more stable tertiary carbocation. Then (1) capture deprotonation gives the major organic product. Four curved arrows total on of 3,3-dimethylcyclohexene. (Draw the intermediates in the blank bra otonation of the alkene gives a secondary...
1. Draw the Most stable chair conformation НО. CI HO OH HOS OH 2. Name following structure: Br 3. Give the major product(s): 1) BHY/THF 2) NaOH, H2O, HẠO Bry/CH,CI;
3. Which cyclohexane molecule would you consider to be the most stable? a.2 b. 1 c. 4 d. 3 4. The molecules below are: a. meso compounds b. structural isomers c. dual comformers d. diastereomers І- н -H Н — - " Н -Н Н Н 2 3 Н 4 Н Н -Н Н - H CH2OH ООН ОН ОН ОН CH,OH HO HO H CH,OH T HO H
18. Draw the product of the following Dieckmann cyclization: 1) NaOCH2CH3 CH3CH2OH 2) H30* 19. Glucosamine is a product of the fermentation of corn and is shown below. Draw the Fischer projection of glucosamine: OH H ОН NH2 OH 20. Draw the most stable chair conformation of the D-idose, whose Fisher projection is shown below. Is it an a-or B-anomer? CHO HO -H H- -OH HO Н H -OH CH2OH
1) OsO. Pyridine 2) NaHSO, H,0 (show stereochemistry NaOH ethanol OH HIO он HO, THE 74) Synthesize the molecule below starting with acetylene (ethyne). List all reagents used. Show products after each proposed step. (6 points) 75) The following is an E2 reaction. Indicate the product. You MUST also show both chair conformations and indicate the chair conformation in which the elimination occurs. (5 points) NaOEt EIOH Page 9 of 13
4. Draw the most stable and most unstable Newman Projection for the following molecules using the rotation around the C3-C4 bond (use the IUPAC rules to number the chain) 5. Draw the two chair conformations for each of the following cyclohexane derivatives and then choose the conformation that is the most stable. Br BA 3 3 3 $ 2879 So ya 6. For the following compounds, identify the chiral carbons with an asterisk (*) and for those that are not...
4. Synthesis Reactions. Draw the feature product of the following reactions. (8 x 3 pts) 1. Mg Ph Br 2. CO2 3. H a "NH2 Ph 1. NaOH, CI 2. LAIH b. CHỊCH NHA NaBHgCN, H+ Ph C. Br (excess) NH d NaOH H HO OH H CH e. 1. NaOH H2O NH 2. H+ o= 1. NaOH H2O 2. SOCI N(CH3)2 3 HO
Which of the following is an efficient synthesis for the transformation below? CI 1) NaOH 2) РСС, СН2CI2 3) EtMgBr 4) Na2Cr207, H2SO4, H20 1) Hзо+ 2) PCC, CH2Cl2 3) MeMgBr 4) Hа0 5) Na2Cr207, H2SO4, H20 1) NaOH 2) РСС, СH2CI2 3) MeMgBr 4) H20 5) NaBH4, MeОн 1) NaOH 2) РСС, CH2CI2 3) MeMgBr 4) H20 5) Na2Cr207, H2SO4, H20 Which of the following is an efficient synthesis for the transformation below? H 1) LIAIH4 2) H20 3)...