17. Propose starting materials needed to synthesize each molecule through a Claisen reaction. a. Etor = = COMe = d....
17. Propose starting materials needed to synthesize each molecule through a Claisen reaction. a. Eto = = OME OMe = = Ph = =
10. Propose starting materials needed to synthesize each molecule through an aldol reaction. a. b. c. d. H f. 11. Give the curved arrow mechanism for each Claisen reaction. a. NaOEt a. b. mild H EtO EtO 1 11 continued a. NaOMe MeO b. b. mild H МеO a. NaOEt с. b. mild H
10. Propose starting materials needed to synthesize each molecule through an aldol reaction. من . . ) » سالب = ، د سال دیگر = = مر
16. Give the major organic product of each Claisen reaction. a. NOF: A WHO it heat b. H.H.O. ETO a. NaoMe b. H. H,0,hea MCO- a. NaOE. a. NaOme. O Mco CCH) OMe b. H.H.O, heat 17. Propose starting materials needed to synthesize each molecule through a Claisen reaction. a. F10 1 1 1 d. EOYOE 1 Ph YYY = 1
7. Show the starting materials, conditions, and steps to make each compound via Claisen reaction or Dieckmann cyclization: b OO OME OEt
23.8 Propose the two ester starting materials for the crossed Claisen product shown below. a time love (b) th ОMe in the name + gome (d) OMe thom have 23.8 Propose the two ester starting materials for the crossed Claisen product shown below. NaOME them
22. The mixed Claisen reaction shown provides product in only a trace amount. The starting materials are obtained upon isolation. Why? CO Me CO Me NaOme MeOH CO Me / dil. HCI Ph Y come A. pka of the propyl ester is too high B. there is only one a-proton C. the benzoate ester is resonance stabilized D. pka of the propyl ester is too low 23. Select the product for the reaction shown: NaOH Ph H2O, THE 5 °C...
6) Provide the structures of the starting materials needed to synthesize the molecule below 7) Out of the two starting material identified in question 6 above, which one forms the enolate?
(4) Propose a synthesis of the target molecule from the indicated starting materials. Cau- tion! Long, inefficient syntheses are penalized. & NH (a) [12 points) (b) [12 points) 2 Ph Ph Ph сн. acetophenone All of the carbons in the target must come from acetophenone.
(4) Propose a synthesis of the target molecule from the indicated starting materials. Cau- tion! Long, inefficient syntheses are penalized. لل H NH2 (a) [12 points] CH (b) [12 points] 2 Ph Ph Ph CH acetophenone All of the carbons in the target must come from acetophenone.