The following amino acid sequence is observed in an alpha-helical segment of a polypeptide: L D E N I K R N A Q L V E Q...
The following amino acid sequence is observed in an alpha-helical segment of a polypeptide:
L D E N I K R N A Q L V E Q Q I R
What pattern, if any, seems to characterize this sequence? Explain why this pattern might be occurring in terms of the 3D structure of the protein.
Homework Answers
Helix-loop-helix pattern may characterize this sequence. Basic amino acids like lysine and arginine are found in this alpha-helical segment. This pattern facilitates DNA binding. So, these patterns are normally found in transcription factors.
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The following amino acid sequence is observed in an alpha-helical segment of a polypeptide: L D E N I K R N A Q L V E Q...
1. The following amino acid sequence is observed in an alpha-helical segment of a polypeptide: L D E N I K R N A Q L V E...
1. The following amino acid sequence is observed in an alpha-helical segment of a polypeptide: L D E N I K R N A Q L V E Q Q I R What pattern, if any, seems to characterize this sequence? Explain why this pattern might be occurring in terms of the 3D structure of the protein. 2. Indicate the probable location of the following amino acid residues in a native globular protein. a) Asp b) Phe c) Met d)...
one sequence contains E-L-K-D-L-S-K-S and the other contains L-R-K-L-E-R-S-L. please draw helical wheels and identify the...
one sequence contains E-L-K-D-L-S-K-S and the other contains L-R-K-L-E-R-S-L. please draw helical wheels and identify the interactions between the 2 wheels. What secondary structure does this form?
a) Draw helical wheels for each of the following two sequences. 1) E-L-K-D-L-S-K-S 2) L-R-K-L-E-R-S-L b....
a) Draw helical wheels for each of the following two sequences. 1) E-L-K-D-L-S-K-S 2) L-R-K-L-E-R-S-L b. In the diagram above show likely interactions between each sequence. C What is the name of the secondary structure this may form
6. (a) Show the arrangement of the groups on the a carbon of the naturally occurring amino acids (draw out the stereoce...
6. (a) Show the arrangement of the groups on the a carbon of the naturally occurring amino acids (draw out the stereocentre). (b) What is the significance of chirality in the biological world? 7. (a) Sh (a) Show the repeating unit of the polypeptide chain in a protein and indicate the peptide bond. (b) What are the following structures of a protein (i) primary, (ii) secondary, (iii) tertiary and (iv) quaternary. 1. Polypeptides are the natural polymer of the naturally...
Explain this question please! Name (4 ofer to the Table of Amino Acids at the beginning of the exam to help solve this problem. Polypeptide I is a 12-mer and has the following amino acid compositi...
Explain this question please!
Name (4 ofer to the Table of Amino Acids at the beginning of the exam to help solve this problem. Polypeptide I is a 12-mer and has the following amino acid composition: Ala, Arg, 2 His, Leu, 2 Lys, 2 Phe, Ser, Thr, Trp Edman degradation of I shows that its N-terminal amino acid is His. Chymotrypsin cleavage of I yields peptide fragments A-D.Trypsin cleavage of I gives peptide fragments E-G. Shown below is the amino...
The amino acid sequence of a portion of a polypeptide is N...Gly-Glu-Met-Tyr-Trp-Lys-Ala...C. I just need help...
The amino acid sequence of a portion of a polypeptide is N...Gly-Glu-Met-Tyr-Trp-Lys-Ala...C. I just need help with part C A. Determine the mRNA sequence encoding this polypeptide fragment. 5'-G-G-N-G-A-Pu-A-U-G-U-A-Py-U-G-G-A-A-Pu-G-C-N-3' B. Determine the DNA template strand sequence corresponding to the mRNA above. 5' N-G-C-Py-T-T-C-C-A-Pu-T-A-C-A-T-Py-T-C-N-C-C- 3' C. Determine the DNA coding strand sequence corresponding to the template strand above. Express your answer as a sequence of nucleotides separated by dashes. Use N to represent any nucleotide (A, T, C or G), Pu...
questions e-f and g.and k. a) Use the 3 letter symbols for a 6 amino acid...
questions e-f and g.and k.
a) Use the 3 letter symbols for a 6 amino acid peptide chain containing at least one polar and at least one acidic or basic amino acid. (All at physiological pH.) Asp - Gly-Glu-Tyr- Phe- Ala OM b) Draw the primary structure with its peptide bonds, side chains, etc. in the correct order. CH3 NH - E-N -CH. - CH - C- 2-I U=0 -ch- & N-chi- CH₃ CH ₂ Coo CH н My Coo...
1) Which of the following is an amino acid? A) e R-CH-CH2-C00R -CH-CooR -CH-C-CO ile R-CH-C-NH3...
1) Which of the following is an amino acid? A) e R-CH-CH2-C00R -CH-CooR -CH-C-CO ile R-CH-C-NH3 R-C=CH-Coo NH3 NH3 NH3 ONH 3 D) coo B) E) 2) Which of the following amino acids has a sulfur in the R group? A) serine B) cysteine C) asparagine D) tyrosine E) leucine 3) Which of the following terms describes the side chain of valine? A) acidic B) basic C) charged, polar D) uncharged, polar E) nonpolar 4) Which of the following is...
26. Which of the following classification does not match the amino acid side chain A) Contains an basic group/ lysi...
26. Which of the following classification does not match the amino acid side chain A) Contains an basic group/ lysine B) It is polar C) Forms disulfide bond/ cysteine D) Forms hydrogen bonds with neighbors/ alanine serine 27. All amino acids found in proteins are L-amino acids EXCEPT the achiral. A) glutamate B) Lysine C) glyeine D) Alamine 28. The plH at which the positive and negative charges of an amino acid balance each ofher is called the A) isotonic...
Overview The purpose of this activity is to help the students to understand how replication, tran...
TranslationOverview:The purpose of this activity is to help the students to understand how replication, transcription, and translation are connected. Students will use a sequence from a bacterial gene that confers resistance to antibiotics (carbapenems). They will be asked to apply the knowledge obtained in the class lecture to (1) find the promoter in the sequence, (2) determine the amino acid sequence of a fragment of the polypeptide, (3) "reverse translate" a fragment of the polypeptide, and (4) identify mutations in...
a) Draw helical wheels for each of the following two sequences. 1) E-L-K-D-L-S-K-S 2) L-R-K-L-E-R-S-L b. In the diagram above show likely interactions between each sequence. C What is the name of the secondary structure this may form
6. (a) Show the arrangement of the groups on the a carbon of the naturally occurring amino acids (draw out the stereocentre). (b) What is the significance of chirality in the biological world? 7. (a) Sh (a) Show the repeating unit of the polypeptide chain in a protein and indicate the peptide bond. (b) What are the following structures of a protein (i) primary, (ii) secondary, (iii) tertiary and (iv) quaternary. 1. Polypeptides are the natural polymer of the naturally...
Explain this question please!
Name (4 ofer to the Table of Amino Acids at the beginning of the exam to help solve this problem. Polypeptide I is a 12-mer and has the following amino acid composition: Ala, Arg, 2 His, Leu, 2 Lys, 2 Phe, Ser, Thr, Trp Edman degradation of I shows that its N-terminal amino acid is His. Chymotrypsin cleavage of I yields peptide fragments A-D.Trypsin cleavage of I gives peptide fragments E-G. Shown below is the amino...
questions e-f and g.and k.
a) Use the 3 letter symbols for a 6 amino acid peptide chain containing at least one polar and at least one acidic or basic amino acid. (All at physiological pH.) Asp - Gly-Glu-Tyr- Phe- Ala OM b) Draw the primary structure with its peptide bonds, side chains, etc. in the correct order. CH3 NH - E-N -CH. - CH - C- 2-I U=0 -ch- & N-chi- CH₃ CH ₂ Coo CH н My Coo...
1) Which of the following is an amino acid? A) e R-CH-CH2-C00R -CH-CooR -CH-C-CO ile R-CH-C-NH3 R-C=CH-Coo NH3 NH3 NH3 ONH 3 D) coo B) E) 2) Which of the following amino acids has a sulfur in the R group? A) serine B) cysteine C) asparagine D) tyrosine E) leucine 3) Which of the following terms describes the side chain of valine? A) acidic B) basic C) charged, polar D) uncharged, polar E) nonpolar 4) Which of the following is...
26. Which of the following classification does not match the amino acid side chain A) Contains an basic group/ lysine B) It is polar C) Forms disulfide bond/ cysteine D) Forms hydrogen bonds with neighbors/ alanine serine 27. All amino acids found in proteins are L-amino acids EXCEPT the achiral. A) glutamate B) Lysine C) glyeine D) Alamine 28. The plH at which the positive and negative charges of an amino acid balance each ofher is called the A) isotonic...
TranslationOverview:The purpose of this activity is to help the students to understand how replication, transcription, and translation are connected. Students will use a sequence from a bacterial gene that confers resistance to antibiotics (carbapenems). They will be asked to apply the knowledge obtained in the class lecture to (1) find the promoter in the sequence, (2) determine the amino acid sequence of a fragment of the polypeptide, (3) "reverse translate" a fragment of the polypeptide, and (4) identify mutations in...
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