Oorai Which is the better leaving group in protic solvent? 1. Which is the better leaving group in aprotic solvent?...
Is Sulfuric Acid a hydroxylic or polar aprotic solvent? In Sulfuric Acid, which is a better nucleophile? Cl- or Br-? Why? And is DMSO a hydroxylic or polar aprotic solvent? In DMSO, which is the better nucleophile? Cl- or Br-? Why?
Question 15 Which of the following is not a condition for optimum SN 1 reaction? aprotic solvent weak base/ good leaving group carbocation protic solvent Question 16 Which of the following is not a condition for optimum S2 reaction? aprotic solvent strong base / good leaving group carbocation protic solvent
5. Circle the better a) acid CH3OH CHiNH or b) nucleophile in protic solvent CI or c) base CH3S CH3O or 6. Write out the mechanism for the following elimination reaction. Show all steps am arrows, Be sure to show all organic products, indicating which is major/minor. Br H2O+ 7. Write out the mechanism for the following reaction. Show all steps and use cur НО +Br2
In a polar aprotic solvent, which nucleophile will be more reactive? H2O or OH- I know that in a protic solvent its OH- but is it the opposite from polar aprotic?
2. Circle the better leaving group in each pair. SH : ОН Нон HO O Br CH3 3. Circle the stronger nucleophile in each pair. НОн ОН SH HO N H H CH3 .N H ОН OH 2. Circle the better leaving group in each pair. SH : ОН Нон HO O Br CH3 3. Circle the stronger nucleophile in each pair. НОн ОН SH HO N H H CH3 .N H ОН OH
13. Consider the nucleophiles, F, Cl, Br, and I. In a polar, aprotic solvent, which should be most reactive? WHY? (2) 14. Consider the nucleophiles, F', Cl, Br, and I. In a polar, protic solvent, which should be most reactive? WHY? (2)
questions 7. Why are polar protic solvents preferred for Syl reactions? A. Solvent ionizability B. Hydrogen bonding C.Heat Capacity D.Both A and B E.Both B and C ene chloride)? 8. Why is triflate (A) a better leaving group then tosylate (B) OSICF В A A. Atomic Size B. Resonance C. Hybridization D.Polarizability E. Inductive Effects E 9. Which compound is the stronger Base? A. Lithium Hydroxide B. Sodium Acetate C. Triethyl amine D. Potassium tert-butoxide E. Water 10. What is...
2. (a) For the following reaction, what solvent would favor SN2 (protic or aprotic)? Provide one example of the appropriate solvent. (b) Please explain why you chose your answer for (a). (CH3)3 + CH31 acetone CI oo. cHS Na DMSO + CHES Na DMSO V + oH Ethanoi NH2 + HOANH, CH31 acetone Өон OH (R)-3-bromo-3-methylhexane Previous Next Dashboard Calendar To Do Notifications
3. What product is formed when 1-bromopropane reacts with each of the following nucleophiles? он H2N CH3S HS CHо 4. Which member of each pair is the better nucleophile? Which is the better leaving group? Best nucleophile? Best leaving group Н:О or HO NH3 or H2O H2O or H2S HO or HS or Br Cl or Br
I nucleophile substitution. 7.8 Which is the better leaving group in each pair? a a, b, NH, NH, C. HẠO, HAS 7.9 Which molecules contain good leaving groups? a. CH CH.CH,Br b . CH,CH,CH,OH . CH.CH,OH, d. CH.CH Does the equilibrium favor the reactants or products in each substitution reaction? a. CH,CH-NH, + Br -- CH,CHBr + NH b. n + ON ~ ON + r 7.6 Identify the nucleophile and leaving group and draw the products of each reaction...