Question

5. Which of the following parts of the IgG molecule are not involved in binding to an antigen? A) Fab B Fc C) Heavy chain D) Light chain E) Variable domain 6. Three membrane receptor proteins bind tightly to a hormone. Based on the data in the table below, (a) what is the Ka for hormone binding by protein 2? (Include appropriate units.) (b) Which of these proteins binds most Ka for all three proteins tightly to this hormone? (c) convert Kd Hormone concentration (nM) Protein 3 Protein 1 Protein 2 0.2 0.048 0.29 0.17 0.5 0.11 0.5 0.33 1 0.2 0.67 0.5 0.89 0.95 0.5 0.8 10 0.71 0.91 20 0.83 0.97 0.95 50 0.93 0.99 0.98 HM 3200A Page

Answer 1

Ans.5) Option B : Fc

Explanation : Fc is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. Fab is "antigen-binding" region of antibody , it is composed of one constant and one variable domain from each heavy and light chain of the antibody ,