Question

Problem i: Indicate the stereo centers of stereo centers of the following natural produs natural product (by placing a star next to them): Paclitaxel (also known as Taxol) Problem II: For each of the following molecules, indicate if it is chiral or not chiral Problem III: Draw the enantiomers of the following molecules:

Answer 1

PROBLEM I A carbon is considered to be chiral if it has all four substituents different from one another. A molewle having a chical centre is said to have a stereogenic at that carbon. So, the stereogenic centers of Taxol are as followed en Å. | fb : 7 PROBLEM I W 1 Achiral due to absence of Chical conters, Achiral due to absence of chiral centers. though it has two chim! centers, the presence of a symmetry element renders the molewk, on the whole aachiral - PROBLEM I An enantiomer is a compound that has the exact opposite configuration at all chiral centers in a carbon. HO HOOL