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The partition coefficient of a drug was determined in two different solvent systems: A. Chloroform/water and...
In drug discovery, the value “log P” (the log of the octanol-water partition coefficient) is often...
In drug discovery, the value “log P” (the log of the octanol-water partition coefficient) is often used as an estimate of the lipophilicity of a potential new drug. log P = log([solute]octanol/[solute]water) The log P value for nicotine is 1.09. If 20 mL of 0.10 g/mL nicotine solution in water is extracted with 20 mL of octanol, how much nicotine is removed from the water layer into the octanol layer? If the same water solution is extracted with (2 x...
If the partition coefficient of a drug between an organic solvent and water is 5, how...
If the partition coefficient of a drug between an organic solvent and water is 5, how many mg of the drug is extracted from a 120 ml of 2% aqueous solution if it was extracted with 60 ml of the organic let mass of compound insolution = 4mg
Question / Not yet answered Marked out of The partition coefficient Pag question Select one: a....
Question / Not yet answered Marked out of The partition coefficient Pag question Select one: a. is a value that measures the propensity of a compound to dissolve in a polar solvent versus a nonpolar solvent b. is determined using two solvents that are immiscible c. is often determined using octanol and water d. can assist with selecting the best solvent when doing an extraction e, all of the above Question 8 The log of the partition coefficient can used...
If the Partition Coefficient for Benzoic Acid in one mL each of Water and Methylene Chloride...
If the Partition Coefficient for Benzoic Acid in one mL each of Water and Methylene Chloride is 2.10, is there more Benzoic Acid in the Water layer or the Methylene Chloride layer? A) If you have one mL each of Water and Methylene Chloride in a vial, which layer is on the top? B) If the same experiment is repeated with benzoic acid between ether and water, which layer would be the top and which layer would be the bottom....
1.) What percent recovery could be expected if 1.000 g of caffeine was initially dissolved in...
1.) What percent recovery could be expected if 1.000 g of
caffeine was initially dissolved in 120 mL of water and then
extracted with a single 80 mL portion of ethyl acetate?
2.) What percent recovery could be expected if 1.000 g of
caffeine was initially dissolved in 120 mL of water and then
extracted as per the protocol given in the lab manual?
3.) Percent recovery and percent yield are occasionally used as
if they are interchangeable terms. They...
5) Two ideal gas systems undergo reversible expansion under different conditions starting from the same P...
5) Two ideal gas systems undergo reversible expansion under different conditions starting from the same P and V. At the end of the expansion, the two systems have the same volume. The pressure in the system that has undergone adiabatic expansion is lower than in the system that has undergone isothermal expansion. Explain this result without using equations.
Distinguish between solute and solvent Question Which of the following is not a solution? Select the...
Distinguish between solute and solvent Question Which of the following is not a solution? Select the correct answer below: O air O an alloy of zinc and copper O a mixture of oil and water O potassium permanganate dissolved in water E FEEDBACK MORE INSTRUCTION Content attribution Activity Details MacBook Air a ER Asooh N command 9.3 Solubility Distinguish between solute and solvent Question Choose the option below that is characteristic of a solution Select the correct answer below. O...
Solubility Product Ksp for Ca(OH)2 is determined in two separate experiments, both at the same temperature....
Solubility Product Ksp for Ca(OH)2 is determined in two separate experiments, both at the same temperature. - by titration of hydroxide in a simple saturated solution of Ca(OH)2. - by titration of hydroxide in a 0.01 M CaCl2 solution saturated with Ca(OH)2. Identify which of the following statements is either completely "True" or at least partially "False" (assuming that the activity of each ion is equal to its molar concentration in each instance): a) True False You would expect the value...
Which of the following statements are true about the energy of the two bullet-block systems immediately...
Which of the following statements are true about the energy of the two bullet-block systems immediately after the collisions? (Select all that apply.) (d) The two bullet-block systems have the same total energy. More energy from the bullet went into deforming the block in the first case (bullet in center) than the second (bullet closer to its edge). The same amount of energy went into deforming the block in both cases. The two bullet-block systems have the same translational kinetic...
Question 17 1 pts What solubility properties are important in the selection of a solvent for...
Question 17 1 pts What solubility properties are important in the selection of a solvent for recrystallisation? sparingly soluble in hot solvent and readily soluble in cold solvent readily soluble in both hot and cold solvent sparingly soluble in both hot and cold solvent readily soluble in hot solvent and sparingly soluble in cold solvent Question 18 1 pts How would you modify the procedure given in the Laboratory Manual if you did not know which solvent to use? if...
Question / Not yet answered Marked out of The partition coefficient Pag question Select one: a. is a value that measures the propensity of a compound to dissolve in a polar solvent versus a nonpolar solvent b. is determined using two solvents that are immiscible c. is often determined using octanol and water d. can assist with selecting the best solvent when doing an extraction e, all of the above Question 8 The log of the partition coefficient can used...
1.) What percent recovery could be expected if 1.000 g of
caffeine was initially dissolved in 120 mL of water and then
extracted with a single 80 mL portion of ethyl acetate?
2.) What percent recovery could be expected if 1.000 g of
caffeine was initially dissolved in 120 mL of water and then
extracted as per the protocol given in the lab manual?
3.) Percent recovery and percent yield are occasionally used as
if they are interchangeable terms. They...
5) Two ideal gas systems undergo reversible expansion under different conditions starting from the same P and V. At the end of the expansion, the two systems have the same volume. The pressure in the system that has undergone adiabatic expansion is lower than in the system that has undergone isothermal expansion. Explain this result without using equations.
Distinguish between solute and solvent Question Which of the following is not a solution? Select the correct answer below: O air O an alloy of zinc and copper O a mixture of oil and water O potassium permanganate dissolved in water E FEEDBACK MORE INSTRUCTION Content attribution Activity Details MacBook Air a ER Asooh N command 9.3 Solubility Distinguish between solute and solvent Question Choose the option below that is characteristic of a solution Select the correct answer below. O...
Which of the following statements are true about the energy of the two bullet-block systems immediately after the collisions? (Select all that apply.) (d) The two bullet-block systems have the same total energy. More energy from the bullet went into deforming the block in the first case (bullet in center) than the second (bullet closer to its edge). The same amount of energy went into deforming the block in both cases. The two bullet-block systems have the same translational kinetic...
Question 17 1 pts What solubility properties are important in the selection of a solvent for recrystallisation? sparingly soluble in hot solvent and readily soluble in cold solvent readily soluble in both hot and cold solvent sparingly soluble in both hot and cold solvent readily soluble in hot solvent and sparingly soluble in cold solvent Question 18 1 pts How would you modify the procedure given in the Laboratory Manual if you did not know which solvent to use? if...
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