1. Fill in the missing product. If more than one product is expected, label which is...
1. Give the product(s) of the following reactions. If more than one product is expected, label them as major and minor. Show stereochemistry clearly when important. (3 pts, cach reaction) NBS ~ light он HI H. Na SCH acetone Brlow temp 2. What would be the best way to synthesize the following compound from an alkyl halide using a nucleophilic substitution reaction? (4 pts.)
(24 pts) 3. Predict the product(s) for each reaction. Indicate stereochemistry if known. If more than one product is predicted, circle the one you think would be major. If there is no reaction expected, then indicate NR. а. HaCl.. Br NaCN THF b. Н—Br ether ОН с. CH3 КОН Br THF d. НОСН heat е. PBr3 ОН ether f. ОН NaSCH3 Hо g. cat Br H2SO4 heat ОН h Br H но heat Br
6. Fill in the missing reagents for the following reactions. If more than one step is necessary, indicate according Br (racemic) OH (racemic) Br (racemic) 7. Synthesize the following molecules by providing the correct substrates and/or reagents. Br Br Br
Provide the missing reagents to complete the reactions below, more than one step may be required. 3. (8 pts) Provide the missing reagents to complete the reactions below, more than one step may be required. HO + OH но"
5. Devise a synthesis of each product from the given starting material. More than one step is required. он он OCH а. OH C. Br Br d. (CHa)2CHCH CH-C-CH,Br b. CH-C-CH (CH3,сCI н
13. (15) For each a For each of the following reactions, fill in the missing reagents from the list provided for Wormation of the product shown. Sequential steps, if necessary. should be numbered. Reagents can be used more than once. Reagent List: H2 C H2O2 = NaH PBT OCI NaBH. Pd/C NaOH BH2O HO HgCl2 Pd/Caco, Br2 HBr H2O (HOAC) (MCPBA) (pyridine) (Msch) por -Cl menos de plaqueta don -он i н он
provide the missing reagent(s) for the following synthesis problems. if more than one step is required, be sure to number the reagents to indicate which ones go in each step. if there is more than one step, please draw each synthetic step separately and provide the product of each step. I OH Br you - 5.
Q2. Synthesize the following product from the given starting compounds. This will require more than one step. You may use any organic or inorganic reagent to carry out this synthesis. (8 pts each) Do (you can also use any one C reagent) ОН (you can also use any two carbon reagent)
For questions 1-4, provide the missing reactant(s), reagent(s), or major organic product(s) of each reaction. Only one type of species is missing for each reaction. If you are providing reactant(8) or product(s), be sure to indicate stereochemistry if it is relevant. If you are providing reagents and more than one step is required, be sure to number each step. 1. EtMgBr 2.H20 NH [H] 5. Propose an efficient synthesis for one of the following transformations. Please circle the synthesis you...
2. (30 pts) Fill in missing information for each chemical reactions by adding the reactive organic compound, all products, and/or the reagents needed to complete the reaction. If there is more than one product, label the major and the minor products. Also, name each organic reactant and each organic product. H,SO 140°C OH + HO + H2O Multi-step reaction: Show all reactants, all reaction conditions and reagents, and all intermediates in order to perform the following reaction. Name each organic...