Question

3. Given what you now know, what product(s) would you expect to isolate from this reaction? • Ngô – Br (NaOt-Bu) Specify how each of the following would affect the rate of the reaction. a. Increase the concentration of the base. b. Decreasing the concentration of alkyl halide. 3. Predict the product(s) for each of the E2 elimination reactions below. Identify the major product for each. Y ahoo Br NaOCH heat

Answer 1

In the giren reaction the recetion is elimination and by the E2 mechanson As the base is a burry bere so the reaction pretern E2 pathway, ни The bene remores a ß-it and then to eliminates Whole. process is ina single step and.. rate = kr (substate] [ base] if the conc. of bese increased then the reaction rate increases. If the concentration of the substrate i.e. alkyl halide increases then also the reaction rate increases.

H 3. 3.a. T By CAJ (meron? [B] forminos According to saytzer's sule the most substituted alkene Mo be the major product. - u. A is the maior product. - Br Here there is no ß H. So; no E2 reaction will take place. Rather in the condition nucleo philic substitution reaction may occure. m SN2

For the elimination reaction there must present a H in beta( $\beta$ )position. As in the b question there is no beta H so no elimination reaction rather substitution occurs.