An epidemiologist found five cases of “big toe cancer” in the
Yukon Territory. Because there were only a few cases, the
epidemiologist decided to conduct a matched case-control study to
determine whether shoe size larger than 9 is a risk factor for big
toe cancer. Cases were individually matched to one control for
daily activity, history of athlete’s foot, and history of ingrown
toenails. The following data were gathered:
Shoe size > 9
Pair Case Control
1 Yes No
2 No No
3 No Yes
4 Yes Yes
5 No Yes
A) Compute the proper measure of association.
B) Interpret your results.
C) If you were to investigate a rare cancer in Lynchburg, where might you look for data?
D) What would be necessary legally and ethically to be able to utilize this data set(s)?
An epidemiologist found five cases of “big toe cancer” in the Yukon Territory. Because there were...
An epidemiologist found five cases of “big toe cancer” in the Yukon Territory. Because there were only a few cases, the epidemiologist decided to conduct a matched case-control study to determine whether shoe size larger than 9 is a risk factor for big toe cancer. Cases were individually matched to one control for daily activity, history of athlete’s foot, and history of ingrown toenails. The following data were gathered: Shoe size > 9 Pair Case Control 1 Yes No...
In an epidemiologic study, 147 incident bladder cancer cases were compared to 179 controls selected from the population that gave rise to the cases with respect to smoking history. The data were as follows: Exposure status Disease Status Case Control Total Smoker 90 82 172 Nonsmoker 57 97 154 Total 147 179 326 Perform the appropriate statistical test of the relationship between bladder cancer and smoking history using the attached SAS file. Assume α = 0.05 (two-tailed) and 80%...
Lung Cancer & Smoking Case Study A causal relationship between cigarette smoking and lung cancer was first suspected in the 1920s on the basis of clinical observations. To test this apparent association, numerous epidemiologic studies were undertaken between 1930 and 1960. Two studies were conducted by Richard Doll and Austin Bradford Hill in Great Britain The first was a case-control study begun in 1947 comparing the smoking habits of lung cancer patients with the smoking habits of other patients. The...
All of the following questions are in relation to the following journal article which is available on Moodle: Parr CL, Magnus MC, Karlstad O, Holvik K, Lund-Blix NA, Jaugen M, et al. Vitamin A and D intake in pregnancy, infant supplementation and asthma development: the Norwegian Mother and Child Cohort. Am J Clin Nutr 2018:107:789-798 QUESTIONS: 1. State one hypothesis the author's proposed in the manuscript. 2. There is previous research that shows that adequate Vitamin A intake is required...