Question

Nucleic acid delivery for disease therapy:
Advantages of the technique ( a general description plus examples)
Shortcomings of the technique, if any (a description and examples)

Answer 1

Therapeutic nucleic acids interfere RNA,antisense oligonucleotide and mRNA,it has become popular in the development of virus based gene therapy..It uses brain disease like Alzheimer's disease, immuno deficiency syndrome,coronary heart disease, neurogenerative disease and other genetic disorders.. Deoxyribonucleic acid and ribonucleic acids used in gene therapy..

DNA and RNA interference therapies to treat many human disease, oral delivering nucleic acid therapy is a shortcomings technique option because it is easy to administer, non-invasive and cost effective..only small portion of this doses will travel to the disease site successfully..nanoparticles in microspheres small RNA delivery shows better outcomes for some barriers..It treat colitis in GI system when it travel through a GI tract make favourable downstream anti-inflammatory effects..In future it will treat celiac disease and chronic inflammatory diseases..