Question

Using your knowledge of aspartyl proteases, suggest a plausible explanation why protein activity changes when pH is increased or decreased from pH 4, as shown in the graph below, with data taken from A. Sharma, A. Eapen, S. K. Subbarao. \"Purification and Characterization of a Hemoglobin Degrading Aspartic Protease from the Malarial Parasite Plasmodium vivax,\" The Journal of Biochemistry, 2005, 138(1), p 71-78.

Answer 1