Question

A patient is about to start taking trimethoprim/sulfamethoxazole (Bactrim) to treat a UTI. You should instruct the patient to report which of the following possible indications of serious adverse efect of this drug? Select all that apply 5. 12.

Answer 1

5. The patient is about to start taking Trimethoprim/Sulfamethoxazole(Bactrim) to treat UTI. You should instruct the patient to report which of the following possible indications of the serious adverse effect of this drug?

Trimethoprim/sulfamethoxazole may cause thrombocytopenia, leukopenia, and other blood dyscrasias. Patients must understand the need to report a sore throat, fever, bruising, or other indications of infection, anemia, or bleeding tendencies. Trimethoprim/sulfamethoxazole is unlikely to cause dry mouth, although it can alter taste sensations. This drug treats urinary tract infections, so it should help resolve the symptoms like urinary frequency and urgency, not cause them. Trimethoprim/sulfamethoxazole is more likely to cause muscle or joint pain than headaches.

So here the answer is A Sore throat, Muscle or Joint pain

6. When talking with the patient about taking rifampicin for TB treatment be sure to instruct the patient to report which of the following possible indications of a serious adverse effect of this drug?

Rifampin can cause liver toxicity and hepatitis, so be sure to monitor liver enzymes during therapy and instruct patients to report abdominal pain, nausea, and jaundice. Rifampin can cause lethargy, drowsiness, and confusion. It is unlikely to cause insomnia. Rifampin can cause a red-orange discoloration of urine, saliva, tears, and sweat, but it is unlikely to cause sweating. Rifampin can cause ataxia, but it is unlikely to cause tremors.

So here the answer is Jaundice

11. An HCP is caring for a patient who is about taking isoniazid to treat TB. The patient should report which of the following adverse effects of the drug?

Numbness of the hands, Dizziness, Jaundice

12. A patient is taking prednisolone for his rheumatoid arthritis and is about to take ciprofloxacin to treat a UTI. Recognizing the adverse effects of ciprofloxacin?

Tendon pain

It can cause an Achilles tendon to rupture, especially in patients who take glucocorticoids or in older adults, thus the patient may experience tendon pain