Explain why it is important to use the following: a) randomization b) replication c) control groups
Why is randomization important to assignment in an RCT? Select one: a. It enables blinding/masking b. So causation may be extrapolated from results c. It balances out individual characteristics between groups. d. A and C
●Explain when randomization is not possible because of ethical or practical reasons ●Understand why estimating the counterfactual is more problematic without randomization ●Describe basic strengths and weaknesses of common observational approaches to estimatingcounterfactuals, such as before-after designs, simultaneous control groups, and combined designs. ●Understand the importance of identifying causal mechanisms and theory for making causal inferences innon-randomized studies.
Explain why telomeres are important by using all of the terms below: -Linear replication -DNA polymerase -Okazaki fragment -Chromosome
Explain the concept of empowerment with minority groups and community health problems. Why is this important?
Explain the concept of empowerment with minority groups and community health problems. Why is this important?
Support groups are separate from clinical therapy groups. Why is it important for substance use disorder counselors to know what happens in non-clinical support groups? How could this knowledge benefit treatment?
Define the followings and give the reason why they are very important experimental design features in quality improvement Replication Randomization Blocking Experimental unit Factor Levels Treatment
Methylation • Add-CH3 groups to a few bases on DNA Why? 1. Control gene expression 2. Initiation of DNA replication 3. Distinguish self DNA from foreign DNA
Explain why modelling is an important tool for designing control systems. Briefly describe a typical design procedure for control systems which employs modeling.
4a. Define semi-conservative DNA replication. 4b. Explain why Recombinational Repair of thymidine dimers absolutely requires active DNA replication. 5a. Explain how the Ames Test works to identify whether a novel chemical (compared to water) is a DNA mutagen. b. Below, draw the plate results that would allow you to conclude that this novel chemical was in fact a mutagen compared to a plate with water as a negative control.