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Methylation • Add-CH3 groups to a few bases on DNA Why? 1. Control gene expression 2. Initiation of DNA replication 3. Distin
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Answer #1

Methylation on DNA is majorly used for three purpose-

1)- To control the gene expression- methylation is an epigenetic modification of DNA. Methylated DNA is generally transcriptionally inactive. Methylated regions on DNA are condensed and packed tightly to give rise heterochromatin, transcriptionally inactive region of DNA. Methylation is also used in X-chromosome inactivation.

2)- To distingeus between self and non-self DNA- Bacterial endonuclease differentiate between self and viral DNA and cleave selectively viral DNA because viral DNA is unmethylated while bacterial DNA is methylated.

3)- In repair- methylation help the repair machinery to distinguish between old/template DNA and newly replicated DNA.

So option 1 and 3 is correct

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