Question

The carbonyl group of an aldehyde or ketone may be reduced via several different methods. Select all viable methods for aldehyde/ketone reduction. Na2Cr2O7 and H2SO4 Wolff-Kishner method Baeyer-Villiger method NH3, H2, and Raney Ni 1) LiAIH4, 2) H20 Clemmensen method KMnO4 and H2SO4 Of the reduction methods, which one would be best performed under acidic conditions? Clemmensen method Na2Cr2O7 and H2SO4 NH3, H2, and Raney Ni KMnO4 and H2SO4 Baeyer-Villiger method Wolff-Kishner method LiAIH4, 2) H20

Need help on both A) and B).

Answer 1

Reduction of aldehydes and ketones with LiAlH4 is as follows: он formaldehyde methanol он LiAlH4 H3C CH acetaldehyde ethanol он H3C CH propan-2-one propan-2-cl Wolff-kishner reduction: Reaction of aldehydes or ketones with hydrazine produces a hydrazone. The reaction is as follows: NH H2N NH + H20 Aldehyde or ketone propan-2-ylidenehydrazine Reaction with a base and heat converts hydrazone to an alkane. The reaction is as follows: NH KOH Heat propane

Clemmensen reduction: The reaction of aldehyde or ketones with zinc amalgam in concentrated hydrochloric acid, which reduces the aldehyde or ketone to a hydrocarbon. is called clemmensen reduction. The reaction is as follows: Zn(Hg), HCI propan-2-one propane Reduction in presence of raney Ni: NH3, H2 Raney Ni cyclohexanone 1,1-dimethylcyclohexane mensen works best in a highly acidic environment.