Autosomal dominant mutations appears in both sexes with equal frequency and both sexes are capable of transmitting these mutations to offsprings therefore do not skip generations.
In above case, there is no sign of dominant mutation in 1st and 2nd generation so when we see diseased III3, we can say that either mutations has occurred spontaneously or the child is adopted. Another case of switching of child at birth also play the role in conclusion so answer should be D.
under what circumstances is it possible for III-3 to be affected by an autosomal dominant mutation?...
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