Identify the products of the reaction between: a. t-butyl chloride and sodium ethoxide b. sodium t-butoxide...
Malonic ester (diethyl malonate) is treated successively with sodium ethoxide (1 eq.), ethyl bromide, potassium tert-butoxide, isobutyl chloride, hot aqueous NaOH HCI, and heat. What is the final product? 6-Methylheptanoic acid • 2-Ethyl-3-methylpentanoic acid HE Ethylisobutylmalonic acid 4-Ethyl-2-methylpentanoic acid 2 Ethyl-4-methylpentanoic acid
2. Why anhydrous sodium sulfate is added to the t-butyl chloride in the purification process? Could solid sodium hydroxide be used instead of anhydrous sodium sulfate? 3. The reaction from t-butyl alcohol and HCl gives t-butyl chloride. Is it SN1 or SN2 reaction and why?
Question 9 10 pts Predict the ether product of each reaction below. A) sodium (S)-2-butoxide + iodoethane B) sodium (R)-2-butoxide + iodoethane C) sodium ethoxide + (S)-2-iodobutane D) sodium ethoxide + (R)-2-iodobutane [Choose] [Choose ] [Choose] [Choose
in the SN1 reaction of t-butyl chloride with ethanol. When more t-butyl chloride is added as a reactant, the rate of the reaction decreases (the reaction becomes slower). Why?
14. Which of the following reagents should be used to prepare tert-butyl ethyl ether a) tert-butyl bromide and sodium ethoxide b) tert-butyl alcohol and ethyl bromide c) tert-butyl alcohol and ethanol d) potassium tert-butoxide and ethyl bromide 15. What is the major organic product obtained from the following reaction? A) 1 B) 2 C) 3 D) 4 16. What product is formed when methyloxirane is treated with ethylmannesium bromide followed by treatment with aqueous acid? A) 1-pentanol B) 2-pentanol C)...
1.1 What is the equation for the rate of formation of tert-butyl
alcohol from the reaction of tert-butyl bromide (t-BuBr) with water
by an SN1 mechanism?
A. Rate= k[t-BuBr]
B Rate=k[ t-BuBr][H2O]
C. Rate=k[ H2O]
D. Rate=k[t-BuBr]^2
1.2 What is the equation for the rate of formation of
1-iodobutane from the reaction of 1-chlorobutane (BuCl) with NaI by
an SN2 mechanism?
A. Rate=k[BuCl]
B. Rate=k[BuCl][NaI]
C. Rate=k[NaI]
D. Rate=k[BuCl]^2
1.3 What is the equation for the rate of formation of...
12. In a synthesis of isopropyl pyridine, the 3-methyl-2- presence of sodium ethoxide to give a dicarbonyl compo NaOCH.CH opropyl pyridine, the 3 with ethyl formate in the 0 ethyl formate 3-methyl-2-butanone a) In the first step of the mechanism, sodiu alpha position to form an enolate. Complete the as necessary (4 points) step of the mechanism, sodium ethoxide deprotonates 3-methyl-2-buthone at the O form an enolate, Complete this reaction with curly arrows drawing in H atoms b) Why is...
18.16 What is the product of the reaction of 2-bromoethane with potassium tert-butoxide? Why is it that little substitution occurs this reaction? 18.17 What is the major product of the reaction of 2-iodopropane with sodium ethoxide?
For SN1 solvolysis of t-butyl chloride, rank the solvents from
fastest reaction to slowest reaction.
For SN1 solvolysis of t-butyl chloride, rank the solvents from fastest reaction to slowest reaction. ethanol water acetic acid formic acid methanol
Predict the products
Chlorocyclopentane and sodium ethoxide in methanol.