When a folded protein in solution is heated to a high enough temperature, its polypeptide chain will unfold to become the denatured protein−a process known as “denaturation.” The temperature at which most of the protein unfolds is called the “melting” temperature. The melting temperature of a certain protein is found to be 63°C, and the enthalpy of denaturation is 510 kJ/mol. Estimate the entropy of denaturation, assuming that the denaturation is a single-step equilibrium process; that is, folded protein ⇄ denatured protein. The single polypeptide protein chain has 98 amino acids. Calculate the entropy of denaturation per amino acid.
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