Problem

It is sometimes necessary to prepare isotopically labeled samples of organic substances fo...

It is sometimes necessary to prepare isotopically labeled samples of organic substances for probing biological transformations and reaction mechanisms. Various sources of the radioactive mass-14 carbon isotope are available. Describe synthetic procedures by which benzoic acid, labeled with 14C at its carbonyl carbon, could be prepared from benzene and the following l4C-labeled precursors. You may use any necessary organic or inorganic reagents.

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Solutions For Problems in Chapter 18