The sites on a protein, which is complimentary to the shape, size, and charge, the hydrophilic or hydrophobic character of a messenger is generally known as the binding site. The messenger binds to this binding site. It is analogous to that of the messenger. When the messenger fits into its receptor binding site on the protein by the induced fit mechanism, it ‘switches on’ the receptor molecule and a message is received.
It is then followed by the separation of the messenger from its receptor binding site of the protein. On the other hand, the binding site is assumed to contain the binding regions that have a functional group complimentary to the binding groups of the messenger.
The messenger fits into the binding site such that intermolecular interactions take place between the binding groups of a messenger and binding regions of the receptor present on a protein.
The functional groups located on the messenger involved in bonding with the binding regions present on the protein’s receptor binding site are commonly known as the binding groups. The shape of the binding site of receptor on protein can alter due to the intermolecular interactions of the binding groups and binding regions.
This results in an induced fit model. The interactions are not enough to hold the messenger tightly, thus after carrying a message; the messenger leaves the receptor with dissociation of intermolecular bonding or interactions.