The amino acid sequences of peptide fragments obtained from a normal protein and from the same protein synthesized by a defective gene were compared. They were found to differ in only one peptide fragment; their amino acid sequences are shown here:
Normal: GIn-Tyr-Gly-Thr-Arg-Tyr-Val
Mutant: Gln-Ser-Glu-Pro-Gly-Thr
a. What is the defect in DNA?
b. It was later determined that the normal peptide fragment is an octapeptide with a C-terminal Val-Leu. What is the C-terminal amino acid of the mutant peptide?
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