Problem

The 2′3′-cyclic phosphodiester, which is formed when RNA is hydrolyzed Figure, reacts with...

The 2′3′-cyclic phosphodiester, which is formed when RNA is hydrolyzed Figure, reacts with water, forming a mixture of nucleotide 2′- and 3′-phosphates. Propose a mechanism for this reaction.

Figure Cleavage of RNA by the 2'-OH group. RNA is thought to undergo cleavage 3 billion times faster than DNA.

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Solutions For Problems in Chapter 20