(a) Lactic acid has a pKa of 3.9. What is the [lactate]/[lactic acid] ratio at the pH of blood (7.4)?
(b) A 0.1 M solution of lactic acid in water has a pH of 2.5. What is the [lactate]/[lactic acid] ratio in this solution?
Sample Solution (a) Use the Henderson-Hasselbalch relationship to calculate the ratio of the concentration of the conjugate base (lactate) to the acid (lactic acid).
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