Problem

Write an equation showing the preparation of the following amides from the indicated carbo...

Write an equation showing the preparation of the following amides from the indicated carboxylic acid derivative:

(a)


(b)


(c)

Sample Solution (a) Amides of the type RC(O)NH2 are derived by acylation of ammonia.

Two molecules of ammonia are needed because its acylation produces, in addition to the desired amide, a molecule of hydrogen chloride. Hydrogen chloride (an acid) reacts with ammonia (a base) to give ammonium chloride.

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