In response to signals from the nervous system, the hypothalamus secretes a polypeptide ho...

In response to signals from the nervous system, the hypothalamus secretes a polypeptide hormone known as gonadotropin- releasing factor (GnRF), which stimulates the pituitary gland to release other hormones into the bloodstream.

Gonadotropin-releasing factor(GnRF) is secreted by the hypothalamus.

Two of the hormones are known as gonadotropins, which are the luteinizing hormone (LH) in males, and the follicle- stimulating hormone (FSH) in females. GnRF is a deca- peptide with the following primary structure: Glu-His-Trp- Ser-Tyr-Gly-Leu-Arg-Pro-Gly.

a. What is the N-terminal amino acid in GnRF?

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b. What is the C-terminal amino acid in GnRF?

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c. Which amino acids in GnRF are nonpolar?

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d. Draw the condensed structural formulas at physiological pH for the acidic and basic amino acids in GnRF.

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e. Draw the condensed structural formulas for the primary structure of the first three amino acids starting from the N-terminal amino acid of GnRF at physiological pH.