Problem

a. Locate all the tetrahedral stereogenic centers in discodermoiide, a natural product iso...

a. Locate all the tetrahedral stereogenic centers in discodermoiide, a natural product isolated from the Caribbean marine sponge Discodermia dissotuta. Discodermolide is a potent tumor inhibitor, and shows promise as a drug for treating colon, ovarian, and breast cancers.


b.  Certain carbon-carbon double bonds can also be stereogenic centers. With reference to the definition in Section 5.3, explain how this can occur, and then locate the three additional stereogenic centers in discodermolide.


c.  Considering all stereogenic centers, what is the maximum number of stereoisomers possible for discodermoiide?

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