Artemisinin and mefloquine are widely used antimalarial drugs.
a. Locate the stereogenic centers in both drugs.
b. Label each stereogenic center in mefloquine as R or S.
c. What is the maximum number of stereoisomers possible for artemisinin?
d. How are the N atoms in mefloquine hybridized?
e. Can two molecules of artemisinin intermolecularly hydrogen bond to each other?
f. What product is formed when mefloquine is treated with HCI?
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